Fabrication of electrospun Eugenol/Cyclodextrin inclusion complex nanofibrous webs for enhanced antioxidant property, water solubility, and high temperature stability

Simple item page
buir.contributor.authorUyar, Tamer
buir.contributor.orcidUyar, Tamer|0000-0002-3989-4481
dc.citation.epage466en_US
dc.citation.issueNumber2en_US
dc.citation.spage457en_US
dc.citation.volumeNumber66en_US
dc.contributor.authorCelebioglu A.en_US
dc.contributor.authorYildiz, Z. I.en_US
dc.contributor.authorUyar, Tameren_US
dc.date.accessioned2019-02-21T16:02:12Z
dc.date.available2019-02-21T16:02:12Z
dc.date.issued2018en_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.departmentNanotechnology Research Center (NANOTAM)en_US
dc.description.abstractIn this study, inclusion complexes (IC) of three cyclodextrin derivatives (HP-β-CD, HP-γ-CD, and M-β-CD) with eugenol (essential oil compound) were formed in highly concentrated aqueous solutions and then transformed into self-standing functional nanofibrous webs by electrospinning. The improved aqueous solubility of eugenol was confirmed by phase solubility diagrams, in addition, the phase solubility tests also revealed 1:1 molar ratio complexation between host:guest molecules; CD:eugenol. Even though eugenol has a volatile nature, a large amount of eugenol (∼70-95%) was preserved in eugenol/cyclodextrin inclusion complex nanofibrous webs (eugenol/CD/IC-NW). Moreover, enhanced thermal stability of eugenol was recorded for eugenol/CD/IC-NW (up to ∼310 °C) when compared to pure form of eugenol (up to ∼200 °C). The eugenol/CD/IC-NW exhibited fast dissolving behavior in water, contrary to poorly water-soluble eugenol. It was observed that the complexation between M-β-CD and eugenol was the strongest when compared to other two host CD molecules (HP-β-CD and HP-γ-CD) for eugenol/CD/IC-NW samples. The electrospun eugenol/CD/IC-NW samples have shown enhanced antioxidant activity compared to pure form of eugenol. In summary, cyclodextrin inclusion complexes of essential oil compounds, such as eugenol, in the form of self-standing nanofibrous webs may have potentials for food and oral-care applications due to their particularly large surface area along with fast-dissolving character, improved water solubility, high temperature stability, and enhanced antioxidant activity.en_US
dc.description.provenanceMade available in DSpace on 2019-02-21T16:02:12Z (GMT). No. of bitstreams: 1 Bilkent-research-paper.pdf: 222869 bytes, checksum: 842af2b9bd649e7f548593affdbafbb3 (MD5) Previous issue date: 2018en
dc.description.sponsorshipTelephone: +90-3122908987; E-mail: tamer@unam.bilkent. edu.tr. ORCID Tamer Uyar: 0000-0002-3989-4481 Funding Dr. Uyar acknowledges The Scientific and Technological Research Council of Turkey (TUBITAK)-Turkey (Project # 213M185) for funding this research. A.C. and Z.I.Y. thank TUBITAK-BIDEB for the PhD scholarship. Notes The authors declare no competing financial interest.
dc.identifier.doi10.1021/acs.jafc.7b04312en_US
dc.identifier.issn0021-8561en_US
dc.identifier.urihttp://hdl.handle.net/11693/49978
dc.language.isoEnglishen_US
dc.publisherAmerican Chemical Societyen_US
dc.relation.isversionofhttps://doi.org/10.1021/acs.jafc.7b04312en_US
dc.relation.project213M185
dc.source.titleJournal of Agricultural and Food Chemistryen_US
dc.subjectAntioxidant propertyen_US
dc.subjectCyclodextrinen_US
dc.subjectElectrospinningen_US
dc.subjectEssential oilsen_US
dc.subjectEugenolen_US
dc.subjectInclusion complexen_US
dc.subjectNanofibersen_US
dc.titleFabrication of electrospun Eugenol/Cyclodextrin inclusion complex nanofibrous webs for enhanced antioxidant property, water solubility, and high temperature stabilityen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Fabrication_of_electrospun_Eugenol_Cyclodextrin_inclusion_complex_nanofibrous_webs_for_enhanced_antioxidant_property_water_solubility_and_high_temperature_stability.pdf
Size:
7 MB
Format:
Adobe Portable Document Format
Description:
Full printable version
Download

Collections

Scholarly Publications - UNAM
Scholarly Publications - NANOTAM