Macroporous Surgical Mesh from a Natural Cocoon Composite

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buir.contributor.authorBilican, Ismail
buir.contributor.authorElbuken, Caglar
dc.citation.epage5738en_US
dc.citation.issueNumber18en_US
dc.citation.spage5728en_US
dc.citation.volumeNumber10en_US
dc.contributor.authorChen, Y.-M.
dc.contributor.authorZang, L.-S.
dc.contributor.authorKoc-Bilican, B.
dc.contributor.authorBilican, Ismail
dc.contributor.authorHolland, C.
dc.contributor.authorCansaran-Duman, D.
dc.contributor.authorKaraduman, T.
dc.contributor.authorÇolak, A.
dc.contributor.authorBayır, Y.
dc.contributor.authorHalici, Z.
dc.contributor.authorOzmen, S.
dc.contributor.authorAli, A.
dc.contributor.authorLabidi, J.
dc.contributor.authorElbuken, Caglar
dc.contributor.authorKaya, M.
dc.date.accessioned2023-02-16T08:18:28Z
dc.date.available2023-02-16T08:18:28Z
dc.date.issued2022-04-25
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.departmentGraduate School of Engineering and Scienceen_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.description.abstractRecently, traditional polymer-based surgical meshes have drawn unwanted attention as a result of host tissue complications arising from infection, biocompatibility, and mechanical compatibility. Seeking an alternative solution, we present a hierarchically structured nanofibrous surgical mesh derived from the naturally woven cocoon of the Japanese giant silkworm, termed MothMesh. We report that it displays nontoxicity, biocompatibility, suitable mechanical properties, and porosity while showing no adverse effect in animal trials and even appears to enhance cell proliferation. Hence, we assert that the use of this natural material may provide an effective and improved alternative to existing synthetic meshesen_US
dc.identifier.doi10.1021/acssuschemeng.1c06941en_US
dc.identifier.issn2168-0485
dc.identifier.urihttp://hdl.handle.net/11693/111412
dc.language.isoEnglishen_US
dc.relation.isversionofhttp://dx.doi.org/10.1021/acssuschemeng.1c06941en_US
dc.source.titleACS Sustainable Chemistry and Engineeringen_US
dc.subjectSustainable materialen_US
dc.subjectFibroinen_US
dc.subjectSericinen_US
dc.subjectBiocompatibilityen_US
dc.subjectSurgical meshen_US
dc.subjectTissue engineeringen_US
dc.titleMacroporous Surgical Mesh from a Natural Cocoon Compositeen_US
dc.typeArticleen_US

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Institute of Materials Science and Nanotechnology (UNAM)
Department of Molecular Biology and Genetics
Graduate School of Engineering and Science