A smartphone based surface plasmon resonance imaging (SPRi) platform for on-site biodetection

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dc.citation.epage577en_US
dc.citation.spage571en_US
dc.citation.volumeNumber239en_US
dc.contributor.authorGuner, H.en_US
dc.contributor.authorOzgur, E.en_US
dc.contributor.authorKokturk, G.en_US
dc.contributor.authorCelik, M.en_US
dc.contributor.authorEsen, E.en_US
dc.contributor.authorTopal, A. E.en_US
dc.contributor.authorAyas, S.en_US
dc.contributor.authorUludag, Y.en_US
dc.contributor.authorElbuken, C.en_US
dc.contributor.authorDana, A.en_US
dc.date.accessioned2018-04-12T11:10:22Z
dc.date.available2018-04-12T11:10:22Z
dc.date.issued2017en_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.description.abstractWe demonstrate a surface plasmon resonance imaging platform integrated with a smartphone to be used in the field with high-throughput biodetection. Inexpensive and disposable SPR substrates are produced by metal coating of commercial Blu-ray discs. A compact imaging apparatus is fabricated using a 3D printer which allows taking SPR measurements from more than 20.000 individual pixels. Real-time bulk refractive index change measurements yield noise equivalent refractive index changes as low as 4.12 × 10−5 RIU which is comparable with the detection performance of commercial instruments. As a demonstration of a biological assay, we have shown capture of mouse IgG antibodies by immobilized layer of rabbit anti-mouse (RAM) IgG antibody with nanomolar level limit of detection. Our approach in miniaturization of SPR biosensing in a cost-effective manner could enable realization of portable SPR measurement systems and kits for point-of-care applications.en_US
dc.description.provenanceMade available in DSpace on 2018-04-12T11:10:22Z (GMT). No. of bitstreams: 1 bilkent-research-paper.pdf: 179475 bytes, checksum: ea0bedeb05ac9ccfb983c327e155f0c2 (MD5) Previous issue date: 2017en
dc.embargo.release2019-02-01en_US
dc.identifier.doi10.1016/j.snb.2016.08.061en_US
dc.identifier.issn0925-4005
dc.identifier.urihttp://hdl.handle.net/11693/37329
dc.language.isoEnglishen_US
dc.publisherElsevieren_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.snb.2016.08.061en_US
dc.source.titleSensors and Actuators, B: Chemicalen_US
dc.subjectOptical sensoren_US
dc.subjectPlasmonicsen_US
dc.subjectSurface plasmon resonance imagingen_US
dc.subject3D printersen_US
dc.subjectAntibodiesen_US
dc.subjectBiosensorsen_US
dc.subjectChemical detectionen_US
dc.subjectCost effectivenessen_US
dc.subjectMammalsen_US
dc.subjectPlasmonsen_US
dc.subjectRefractive indexen_US
dc.subjectResonanceen_US
dc.subjectSemiconductor quantum wellsen_US
dc.subjectSignal encodingen_US
dc.subjectSmartphonesen_US
dc.subjectCommercial instrumentsen_US
dc.subjectDetection performanceen_US
dc.subjectEquivalent refractive indexen_US
dc.subjectMobile sensingen_US
dc.subjectOptical discsen_US
dc.subjectRefractive index changesen_US
dc.subjectSurface plasmon resonanceen_US
dc.titleA smartphone based surface plasmon resonance imaging (SPRi) platform for on-site biodetectionen_US
dc.typeArticleen_US

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