Lab-on-a-chip platforms for disease detection and diagnosis

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dc.citation.epage181en_US
dc.citation.spage155en_US
dc.contributor.authorIşıksaçan, Ziya.en_US
dc.contributor.authorGüler, M. T.en_US
dc.contributor.authorKalantarifard, Alien_US
dc.contributor.authorAsghari, Mohammaden_US
dc.contributor.authorElbüken, Çağlaren_US
dc.contributor.editorAltıntaş, Z.
dc.date.accessioned2019-02-21T15:54:26Z
dc.date.available2019-02-21T15:54:26Z
dc.date.issued2018en_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.departmentNanotechnology Research Center (NANOTAM)en_US
dc.descriptionChapter 8
dc.description.abstractThe adaptation of silicon electronics microfabrication technologies to other materials led to the birth of microfluidic systems. These systems allow investigation and control of fluids at micrometer scale. Due to the wide variety of applications of microfluidics, several research groups have been involved in the development of basic microfluidic components. After the development of fundamental fluid handling components, these technologies have been integrated for numerous applications one of which is disease detection and diagnostics. This chapter summarizes the microfluidic platforms that are mature enough for adaptation towards disease detection. The microfluidic platforms were discussed under six categories: continuous flow, paper‐based, microdroplets, digital microfluidics, compact disk‐based, and wearable platforms. Seminal works and recent developments in each category have been presented together with successful commercial examples. It is worth noting that some studies straddle more than one category, therefore, this classification is strictly for the ease of the reader. Each section discusses the benefits of a specific microfluidic platform. Engineering of microfluidic systems lead to lab‐on‐a‐chip (LOC) systems that can be used for diagnostics whether at point‐of‐care as portable systems or at clinical settings as advanced detection systems. The increasing awareness on personalized treatments proves the importance of such democratizing technologies. The increasing market share of microfluidic platforms in nearly all sectors is also an indication of the bright future of microfluidics and lab‐on‐a‐chip systems. The chapter is ended with a future outlook.
dc.identifier.doi10.1002/9781119065036.ch8
dc.identifier.isbn9781119065012
dc.identifier.urihttp://hdl.handle.net/11693/49817
dc.language.isoEnglish
dc.publisherWiley Blackwell
dc.relation.ispartofBiosensors and Nanotechnology: applications in health care diagnostics
dc.relation.isversionofhttps://doi.org/10.1002/9781119065036.ch8
dc.subjectLab‐on‐a‐chip
dc.subjectMicro total analysis systems
dc.subjectMicrofluidics
dc.subjectDiagnostics
dc.titleLab-on-a-chip platforms for disease detection and diagnosisen_US
dc.typeBook Chapteren_US

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Institute of Materials Science and Nanotechnology (UNAM)
Nanotechnology Research Center (NANOTAM)