Browsing by Subject "Surface Functionalization"

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    Design, synthesis and characterization of bioinspired nanomaterials for engineering and biomedicine
    (2014) Ceylan, Hakan
    Nature is an inspirational school for materials scientists. Natural selection process puts a massive pressure on biological organisms giving rise to effective strategies for fabricating materials, which generally outperform their man-made counterparts. Mimicking physical and chemical features of biological materials can greatly aid in overcoming existing design constraints of engineering and medicine. In this dissertation, a reductionist, bottom-up approach is demonstrated to recapitulate biological functionalities in fully-synthetic hybrid constructs. For material design, the potential of short, rationally-designed peptides for programmed organization into nanostructured materials is explored. The resulting nano-ordered materials exhibit multifunctional and adaptive properties, which can be tailored by the information within monomeric peptide sequences as well as the emerging properties upon their self-assembly. In light of these, design, synthesis and characterization of the prototypes of nanostructured functional materials are described in the context of regenerative medicine and biomineralization.
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    SILVER nano-cylinders designed by EBL used as label free LSPR nano-biosensors
    (SPIE, 2011) Cinel, Neval A.; Bütün, Serkan; Özbay, Ekmel
    Localized Surface Plasmon Resonance (LSPR) is based on the electromagnetic-field enhancement of metallic nano-particles. It is observed at the metal-dielectric interface and the resonance wavelength can be tuned by the size, shape, and periodicity of the metallic nanoparticles and the surrounding dielectric environment. This makes LSPR a powerful candidate in bio-sensing. In the present work, the size and period dependency of the LSPR wavelength was studied through simulations and fabrications. The surface functionalization, that transforms the surface into a sensing platform was done and verified. Finally, the concentration dependency of the LSPR shifts was observed. All the measurements were done by a transmission set-up. The study is at an early stage, however results are promising. The detection of specific bacteria species can be made possible with such a detection method. © 2011 SPIE.