Browsing by Subject "Mathematical modeling"
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Item Open Access A planar facility location–allocation problem with fixed and/or variable cost structures for rural electrification(2023-06) Akbaş, Beste; Kocaman, Ayşe SelinOne major impediment to developing countries’ economic growth is the lack of access to affordable, sustainable, and reliable modern energy systems. Even today, hundreds of millions of people live in rural areas and do not have access to essential electricity services. In this study, we present a planar facility location–allocation problem for planning decentralized energy systems in rural development. We consider nano-grid and micro-grid systems to electrify rural households. While micro-grids serve multiple households with a common generation facility, nano-grids are small-scale systems serving individual consumers. The households served by micro-grids are connected to the generation facilities with low-voltage cables, for which we employ a distance limit constraint due to technical concerns, including power loss and allowable voltage levels. In this problem, we minimize the total investment cost that consists of the facility opening and the low-voltage cable costs. In order to capture the diversity of cost structures in renewable energy investments, we consider three versions of the objective function where we incorporate different combinations of fixed and variable cost components for facilities. For this problem, we provide mixed-integer quadratically constrained problem formulations and propose model-based and clustering-based heuristic approaches. Model-based approaches are multi-stage, in which we solve the discrete counterparts of the problem and employ alternative selection methods for the candidate facility locations. Clustering-based approaches utilize faster clustering techniques to identify the type and location of the facilities. We conduct computational experiments on real-life instances from villages in Sub-Saharan Africa and perform a comparative analysis of the suggested heuristic approaches.Item Open Access Community-driven roadmap for integrated disease maps(Oxford University Press, 2018) Ostaszewski, M.; Gebel, S.; Kuperstein, I.; Mazein, A.; Zinovyev, A.; Doğrusöz, Uğur; Hasenauer, J.; Fleming, R. M. T.; Novere, N. L.; Gawron, P.; Ligon, T.; Niarakis, A.; Nickerson, D.; Weindl, D.; Balling, R.; Barillot, E.; Auffray, C.; Schneider, R.The Disease Maps Project builds on a network of scientific and clinical groups that exchange best practices, share information and develop systems biomedicine tools. The project aims for an integrated, highly curated and user-friendly platform for disease-related knowledge. The primary focus of disease maps is on interconnected signaling, metabolic and gene regulatory network pathways represented in standard formats. The involvement of domain experts ensures that the key disease hallmarks are covered and relevant, up-to-date knowledge is adequately represented. Expert-curated and computer readable, disease maps may serve as a compendium of knowledge, allow for data-supported hypothesis generation or serve as a scaffold for the generation of predictive mathematical models. This article summarizes the 2nd Disease Maps Community meeting, highlighting its important topics and outcomes. We outline milestones on the roadmap for the future development of disease maps, including creating and maintaining standardized disease maps; sharing parts of maps that encode common human disease mechanisms; providing technical solutions for complexity management of maps; and Web tools for in-depth exploration of such maps. A dedicated discussion was focused on mathematical modeling approaches, as one of the main goals of disease map development is the generation of mathematically interpretable representations to predict disease comorbidity or drug response and to suggest drug repositioning, altogether supporting clinical decisions.Item Open Access Debris removal during disaster response: a case for Turkey(Elsevier, 2016) Sahin, H.; Kara, B. Y.; Karasan, O. E.Debris occurs from the ruin and wreckage of structures during a disaster. Proper removal of debris is of great importance because it blocks roads and prohibits emergency aid teams from accessing disaster-affected regions. Poor disaster management, lack of efficiency and delays in debris removal cause disruptions in providing shelter, nutrition, healthcare and communication services to disaster victims, and more importantly, result in loss of lives. Due to the importance of systematic and efficient debris removal from the perspectives of improving disaster victims quality of life and allowing the transportation of emergency relief materials, the focus of this study is on providing emergency relief supplies to disaster-affected regions as soon as possible by unblocking roads through removing the accumulated debris. We develop a mathematical model for the problem that requires long CPU times for large instances. Since it is crucial to act quickly in an emergency case, we also propose a heuristic methodology that solves instances with an average gap of 1% and optimum ratio of 80.83%.Item Open Access Feedback control design for subsonic cavity flows(2009) Yuan X.; Caraballo, E.; Little J.; Debiasi, M.; Serrani, A.; Özbay, Hitay; Myatt J.H.; Samimy, M.A benchmark problem in active aerodynamic flow control, suppression of strong pressure oscillations induced by flow over a shallow cavity, is addressed in this paper. Proper orthogonal decomposition and Galerkin projection techniques are used to obtain a reduced-order model of the flow dynamics from experimental data. The model is made amenable to control design by means of a control separation technique, which makes the control input appear explicitly in the equations. A prediction model based on quadratic stochastic estimation correlates flow field data with surface pressure measurements, so that the latter can be used to reconstruct the state of the model in real time. The focus of this paper is on the controller design and implementation. A linear-quadratic optimal controller is designed on the basis of the reduced-order model to suppress the cavity flow resonance. To account for the limitation on the magnitude of the control signal imposed by the actuator, the control action is modified by a scaling factor, which plays the role of a bifurcation parameter for the closed-loop system. Experimental results, in qualitative agreement with the theoretical analysis, show that the controller achieves a significant attenuation of the resonant tone with a redistribution of the energy into other frequencies, and exhibits a certain degree of robustness when operating in off-design conditions.Item Open Access Mathematical and numerical modeling of the effect of input-parameters on the flushing efficiency of plasma channel in EDM process(Elsevier Ltd, 2013) Shabgard, M.; Ahmadi, R.; Seyedzavvar, M.; Oliaei, S.N.B.In the present study, the temperature distribution on the surface of workpiece and tool during a single discharge in the electrical discharge machining process has been simulated using ABAQUS code finite element software. The temperature dependency of material properties and the expanding of plasma channel radius with time have been employed in the simulation stage. The profile of temperature distribution has been utilized to calculate the dimensions of discharge crater. Based on the results of FEM and the experimental observations, a numerical analysis has been developed assessing the contribution of input-parameters on the efficiency of plasma channel in removing the molten material from molten puddles on the surfaces of workpiece and tool at the end of each discharge. The results show that the increase in the pulse current and pulse on-time have converse effects on the plasma flushing efficiency, as it increases by the prior one and decreases by the latter one. Later, the introduced formulas for plasma flushing efficiency based on regression model were utilized to predict the cardinal parameter of recast layer thickness on the electrodes which demands expensive empirical tests to be obtained. © 2012 Elsevier Ltd. All rights reserved.Item Open Access A Mathematical Model for Cholesterol Biosynthesis under Nicotine Exposure(Elsevier B.V., 2016) Gölgeli, M.; Özbay, HitayIn this paper, a mathematical model is considered for analyzing the impact of nicotine exposure to cholesterol biosynthesis. The dynamical model is nonlinear. Its equilibrium points are computed and conditions are provided under which a unique locally stable positive equilibrium exists. Moreover, effect of internal time delays on local stability is also investigated.Item Open Access Multi input dynamical modeling of heat flow with uncertain diffusivity parameter(Taylor & Francis, 2003) Efe, M. Ö.; Özbay, HitayThis paper focuses on the multi-input dynamical modeling of one-dimensional heat conduction process with uncertainty on thermal diffusivity parameter. Singular value decomposition is used to extract the most significant modes. The results of the spatiotemporal decomposition have been used in cooperation with Galerkin projection to obtain the set of ordinary differential equations, the solution of which synthesizes the temporal variables. The spatial properties have been generalized through a series of test cases and a low order model has been obtained. Since the value of the thermal diffusivity parameter is not known perfectly, the obtained model contains uncertainty. The paper describes how the uncertainty is modeled and how the boundary conditions are separated from the remaining terms of the dynamical equations. The results have been compared with those obtained through analytic solution. © Taylor and Francis Ltd.Item Open Access Robot move sequence determining and multiple part-type scheduling in hybrid flexible flow shop robotic cells(Elsevier, 2016) Batur, G. D.; Erol, S.; Karasan, O. E.We focus on the scheduling problem arising in hybrid flexible flow shops which repeatedly produce a set of multiple part-types and where the transportation of the parts between the machines is performed by a robot. The cycle time of the cell is affected by the robot move sequence, part/machine assignments and part sequences. In a hybrid flexible flow shop in which there exist one machine in the first and two machines in the second stage, the problem of determining the best cycle time is modeled as a traveling salesman problem. In order to provide a solution methodology for realistic problem instances, a Simulated Annealing based heuristic is constructed and the problem is solved using two different neighborhood structures. The results are also compared against an effective proposed lower bound value.Item Open Access Rural electrification: An overview of optimization methods(Elsevier Ltd, 2021-12-23) Akbas, B.; Kocaman, Ayşe Selin; Trotter, P. A.; Nock, D.In order to provide “affordable, reliable, sustainable and modern energy for all” by 2030 under Sustainable Development Goal 7 (SDG7), rural electrification needs significant progress as the majority of people without access to electricity reside in rural areas. Optimization methods can play a critical role in this progress, providing an analytical framework to achieve a variety of economic, social, and environmental objectives subject to budget, resources, local demographics and other constraints. This review paper presents the first overview of optimization-based solution methodologies developed or applied for rural electrification. Based on our review, we first propose four archetype problems for rural electrification, namely (i) optimal system configuration and unit sizing, (ii) optimal power dispatch strategy, (iii) optimal technology choice, and (iv) optimal network design. We discuss each problem type, and provide a systematic classification based on the problem objective, proposed solution methodology, components, scale, region as well as their relationship to the different SDG7 components. We reveal research gaps and open questions for future studies for energy researchers and aim to draw the attention of the optimization community to the challenging and unique problems that need urgent attention in this critical area.