Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

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buir.contributor.authorBelkaya, Serkan
dc.citation.epage16en_US
dc.citation.issueNumber6515en_US
dc.citation.spage1en_US
dc.citation.volumeNumber370en_US
dc.contributor.authorZhang, Q.
dc.contributor.authorLiu, Z.
dc.contributor.authorMoncada-Velez, M.
dc.contributor.authorChen, J.
dc.contributor.authorOgishi, M.
dc.contributor.authorBigio, B.
dc.contributor.authorYang, R.
dc.contributor.authorArias, A. A.
dc.contributor.authorZhou, Q.
dc.contributor.authorHan, J. E.
dc.contributor.authorÖzçelik, Tayfun
dc.contributor.authorUğurbil, A. C.
dc.contributor.authorZhang, P.
dc.contributor.authorRapaport, F.
dc.contributor.authorLi, J.
dc.contributor.authorSpaan, A. N.
dc.date.accessioned2021-03-05T17:19:22Z
dc.date.available2021-03-05T17:19:22Z
dc.date.issued2020
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.description.abstractClinical outcomes of human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (COVID-19). Epidemiological studies have identified three risk factors for severe disease: being male, being elderly, and having other medical conditions. However, interindividual clinical variability remains huge in each demographic category. Discovering the root cause and detailed molecular, cellular, and tissue- and body-levelmechanismsunderlying life-threatening COVID-19 is of the utmost biological and medical importance.en_US
dc.description.provenanceSubmitted by Zeynep Aykut (zeynepay@bilkent.edu.tr) on 2021-03-05T17:19:22Z No. of bitstreams: 1 Inborn_errors_of_type_I_IFN_immunity_in_patients_with_life_threatening_COVID-19.pdf: 1408214 bytes, checksum: 9c2d90617359c54e06530ae55670a982 (MD5)en
dc.description.provenanceMade available in DSpace on 2021-03-05T17:19:22Z (GMT). No. of bitstreams: 1 Inborn_errors_of_type_I_IFN_immunity_in_patients_with_life_threatening_COVID-19.pdf: 1408214 bytes, checksum: 9c2d90617359c54e06530ae55670a982 (MD5) Previous issue date: 2020en
dc.identifier.doi10.1126/science.abd4570en_US
dc.identifier.eissn1095-9203
dc.identifier.issn0036-8075
dc.identifier.urihttp://hdl.handle.net/11693/75852
dc.language.isoEnglishen_US
dc.publisherAmerican Association for the Advancement of Scienceen_US
dc.relation.isversionofhttps://dx.doi.org/10.1126/science.abd4570en_US
dc.source.titleScienceen_US
dc.titleInborn errors of type I IFN immunity in patients with life-threatening COVID-19en_US
dc.typeArticleen_US

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