Nanosized delivery systems for tissue regeneration

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buir.contributor.authorGüler, Mustafa O.
dc.citation.epage31en_US
dc.citation.spage7en_US
dc.contributor.authorÇınar, Göksuen_US
dc.contributor.authorMumcuoğlu, Didemen_US
dc.contributor.authorTekinay, Ayşe B.en_US
dc.contributor.authorGüler, Mustafa O.en_US
dc.contributor.editorGüler, Mustafa O.
dc.contributor.editorTekinay, Ayşe B.
dc.date.accessioned2019-04-17T12:48:37Z
dc.date.available2019-04-17T12:48:37Z
dc.date.issued2016-03-11en_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.departmentNanotechnology Research Center (NANOTAM)en_US
dc.descriptionChapter 2en_US
dc.description.abstractThis chapter focuses on advanced delivery of biologics including growth factors (GFs), cytokines, genes, or siRNAs using a variety of nanosized systems for different regeneration applications focusing on bone, cartilage, nervous system, and muscle regeneration strategies. Gene therapy provides permanent genetic alteration, but only transient actions of protein therapeutics can be needed for tissue regeneration applications. The limitations of biologics delivery and alternative strategies for overcoming recent problems are underlined presenting recent examples from the literature. In addition, specific targeting and cellular internalization strategies of biologies delivery for tissue regeneration are discussed for providing future perspectives to the readers in this field. Overall, it is believed that advanced nanosized delivery systems integrated with multicomponent designs will open new opportunities in delivery technologies and strategies for tissue regeneration.en_US
dc.identifier.doi9781118987483.ch2en_US
dc.identifier.doi10.1002/9781118987483en_US
dc.identifier.eisbn9781118987483
dc.identifier.isbn9781118987452
dc.identifier.urihttp://hdl.handle.net/11693/50834
dc.language.isoEnglishen_US
dc.publisherJohn Wiley & Sonsen_US
dc.relation.ispartofTherapeutic nanomaterialsen_US
dc.relation.isversionofhttps://doi.org/10.1002/9781118987483.ch2en_US
dc.relation.isversionofhttps://doi.org/10.1002/9781118987483en_US
dc.subjectCellular internalizationen_US
dc.subjectCytokinesen_US
dc.subjectGene deliveryen_US
dc.subjectNanosized deliveryen_US
dc.subjectProtein therapeuticsen_US
dc.subjectSirna deliveryen_US
dc.subjectSystemic targetingen_US
dc.subjectTargeted deliveryen_US
dc.subjectTissue regenerationen_US
dc.titleNanosized delivery systems for tissue regenerationen_US
dc.typeBook Chapteren_US

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