Safety of nanomaterials

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buir.contributor.authorGüler, Mustafa O.
dc.citation.epage298en_US
dc.citation.spage271en_US
dc.contributor.authorGündüz, Nurayen_US
dc.contributor.authorArslan, Elifen_US
dc.contributor.authorGüler, Mustafa O.en_US
dc.contributor.authorTekinay, Ayşe B.en_US
dc.contributor.editorGüler, Mustafa O.
dc.contributor.editorTekinay, Ayşe B.
dc.date.accessioned2019-04-25T06:18:08Z
dc.date.available2019-04-25T06:18:08Z
dc.date.issued2016-03-11en_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.departmentNanotechnology Research Center (NANOTAM)en_US
dc.descriptionChapter 11en_US
dc.description.abstractThis chapter overviews the attempts in understanding the biocompatibility of nanomaterials and provides an account of how these views changed in light of recent findings, with emphasis on the methodology used in nanotoxicology studies. The excretion and clearance of engineered nanomaterials (ENMs) is discussed in the chapter, but it should be noted that cells themselves respond to ENMs by activating their exocytosis mechanisms, thus extruding or degrading ENMs at the subcellular level. Although the in vitro tests previously outlined in the chapter provide means of predicting the behavior of nanomaterials, it is nonetheless possible that unforeseen in vivo effects may occur. As with any material intended for human use, their safety must first and foremost be investigated to sufficient detail, through both in vitro experiments and animal studies, before they can be administered to human patients.en_US
dc.identifier.doi10.1002/9781118987483.ch11en_US
dc.identifier.doi10.1002/9781118987483en_US
dc.identifier.eisbn9781118987483
dc.identifier.isbn9781118987452
dc.identifier.urihttp://hdl.handle.net/11693/50933
dc.language.isoEnglishen_US
dc.publisherJohn Wiley & Sonsen_US
dc.relation.ispartofTherapeutic nanomaterialsen_US
dc.relation.isversionofhttps://doi.org/10.1002/9781118987483.ch11en_US
dc.relation.isversionofhttps://doi.org/10.1002/9781118987483en_US
dc.subjectBiological identityen_US
dc.subjectCell viabilityen_US
dc.subjectCell‐material interfaceen_US
dc.subjectChemical identityen_US
dc.subjectEngineered nanomaterialsen_US
dc.subjectIntracellular activityen_US
dc.subjectNanotoxicology studiesen_US
dc.subjectProliferationen_US
dc.subjectRisk assessmenten_US
dc.titleSafety of nanomaterialsen_US
dc.typeBook Chapteren_US
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