Antibacterial activity of cyclodextrin-Azo dye inclusion complex encapsulated electrospun polycaprolactone nanofibers

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buir.contributor.authorDemirci, Serkan
buir.contributor.authorÇelebioğlu, Aslı
buir.contributor.orcidDemirci, Serkan|0000-0002-4753-2069
buir.contributor.orcidÇelebioğlu, Aslı|0000-0002-5563-5746
dc.citation.epage10446en_US
dc.citation.issueNumber38en_US
dc.citation.spage10440en_US
dc.citation.volumeNumber6en_US
dc.contributor.authorDemirci, Serkan
dc.contributor.authorÇelebioğlu, Aslı
dc.contributor.authorDemirci, S. K.
dc.contributor.authorİdil, Ö.
dc.date.accessioned2022-01-27T11:58:42Z
dc.date.available2022-01-27T11:58:42Z
dc.date.issued2021-10-12
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.description.abstractPolycaprolactone (PCL) nanofibers incorporating azo dye/γ-cyclodextrin inclusion complex (Azo/γ-CD-IC) were successfully produced. The characteristics of the Azo/γ-CD-IC and PCL/Azo/γ-CD-IC nanofibers were investigated by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). Based on the SEM analysis the prepared nanofiber has a smooth surface with a size diameter below 500 nm. Meanwhile, the thermal stability of Azo was further improved after being embedded into Azo/γ-CD-IC and the PCL/Azo/γ-CD-IC nanofibers. Proton nuclear magnetic resonance (1H-NMR) was used to calculate the molar ratio of Azo/γ-CD. The antibacterial activity of the PCL/Azo/γ-CD-IC and PCL/Azo nanofibers was investigated using colony counting method and bacterial strains of Escherichia coli and Staphylococcus aureus were used. The results indicated that PCL/Azo/γ-CD-IC nanofibers have enhanced antibacterial activity against Escherichia coli and Staphylococcus aureus compared to PCL/Azo owing to inclusion complexation. Therefore, these PCL/Azo/γ-CD-IC nanofibers might have potential applications in the biomedical field.en_US
dc.description.provenanceSubmitted by Samet Emre (samet.emre@bilkent.edu.tr) on 2022-01-27T11:58:42Z No. of bitstreams: 1 Antibacterial_Activity_of_Cyclodextrin-Azo_Dye_Inclusion_Complex_Encapsulated_Electrospun_Polycaprolactone_Nanofibers.pdf: 4929920 bytes, checksum: f104a06df3bcd05a5e2221d391694cfd (MD5)en
dc.description.provenanceMade available in DSpace on 2022-01-27T11:58:42Z (GMT). No. of bitstreams: 1 Antibacterial_Activity_of_Cyclodextrin-Azo_Dye_Inclusion_Complex_Encapsulated_Electrospun_Polycaprolactone_Nanofibers.pdf: 4929920 bytes, checksum: f104a06df3bcd05a5e2221d391694cfd (MD5) Previous issue date: 2021-10-12en
dc.embargo.release2022-10-12
dc.identifier.doi10.1002/slct.202101881en_US
dc.identifier.eissn2365-6549
dc.identifier.urihttp://hdl.handle.net/11693/76838
dc.language.isoEnglishen_US
dc.publisherWiley-VCH Verlag GmbH & Co. KGaAen_US
dc.relation.isversionofhttps://doi.org/10.1002/slct.202101881en_US
dc.source.titleChemistrySelecten_US
dc.subjectAntibacterial activityen_US
dc.subjectAzo compoundsen_US
dc.subjectCyclodextrinsen_US
dc.subjectElectrospinningen_US
dc.subjectInclusion compoundsen_US
dc.subjectNanofibeen_US
dc.titleAntibacterial activity of cyclodextrin-Azo dye inclusion complex encapsulated electrospun polycaprolactone nanofibersen_US
dc.title.alternativeAntibacterial activity of cyclodextrin-Azo dye inclusion complex encapsulated electrospun polycaprolactone nanofibersen_US
dc.typeArticleen_US

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