Probing viscosity via relaxation in magnetic particle imaging

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buir.advisorSarıtaş, Emine Ülkü
dc.contributor.authorÜtkür, Mustafa
dc.date.accessioned2017-01-27T08:30:08Z
dc.date.available2017-01-27T08:30:08Z
dc.date.copyright2017-01
dc.date.issued2017-01
dc.date.submitted2017-01-25
dc.descriptionCataloged from PDF version of article.en_US
dc.descriptionThesis (M.S.): Bilkent University, Department of Electrical and Electronics Engineering, İhsan Doğramacı Bilkent University, 2017.en_US
dc.descriptionIncludes bibliographical references (leaves 36-42).en_US
dc.description.abstractMagnetic Particle Imaging (MPI) is a high-contrast imaging modality with applications such as angiography, stem cell tracking, and cancer imaging. In recent years, MPI was shown to be a potential functional imaging modality through \color MPI" techniques, where responses from different nanoparticles can be distinguished. These techniques can be extended to differentiate environmental conditions or states such as different viscosities. Increased viscosity in vivo was shown to be related with various diseases such as hypertension, atherosclerosis, and cancer. Through color MPI techniques, MPI shows a great promise for mapping viscosity and for helping in the diagnosis of these important diseases. This thesis demonstrates the capability of MPI to map viscosities through an estimation of relaxation time constant of nanoparticles. This capability is verified through an extensive experimental work with a magnetic particle spectrometer (MPS) setup that is custom designed. These experiments are conducted for the biologically important viscosity range between 0.89 mPa.s and 15.33 mPa.s, at four different frequencies (between 250 Hz and 10.8 kHz) and at three different field amplitudes (between 5 mT and 15 mT). The results demonstrate MPI's viscosity mapping capability in a biological range.en_US
dc.description.provenanceSubmitted by Betül Özen (ozen@bilkent.edu.tr) on 2017-01-27T08:30:08Z No. of bitstreams: 1 10136677.pdf: 6372705 bytes, checksum: 4359a5592b95ee6093162028960d647a (MD5)en
dc.description.provenanceMade available in DSpace on 2017-01-27T08:30:08Z (GMT). No. of bitstreams: 1 10136677.pdf: 6372705 bytes, checksum: 4359a5592b95ee6093162028960d647a (MD5) Previous issue date: 2017-01en
dc.description.statementofresponsibilityby Mustafa Ütkür.en_US
dc.embargo.release2018-01-25
dc.format.extentxv, 45 leaves : illustrations, charts (some color)en_US
dc.identifier.itemidB155010
dc.identifier.urihttp://hdl.handle.net/11693/32620
dc.language.isoEnglishen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMagnetic particle imagingen_US
dc.subjectViscosity mappingen_US
dc.subjectRelaxationen_US
dc.subjectMagnetic nanoparticlesen_US
dc.titleProbing viscosity via relaxation in magnetic particle imagingen_US
dc.title.alternativeManyetik parçacık görüntülemede relaksasyon yoluyla viskozite ölçümüen_US
dc.typeThesisen_US
thesis.degree.disciplineElectrical and Electronic Engineering
thesis.degree.grantorBilkent University
thesis.degree.levelMaster's
thesis.degree.nameMS (Master of Science)

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