Near IR absorbing bodipy-functionalized SPIONs: a potential magnetic nanoplatform for diagnosis and therapy

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dc.citation.epage903en_US
dc.citation.issueNumber6en_US
dc.citation.spage899en_US
dc.citation.volumeNumber86en_US
dc.contributor.authorErtem, E.en_US
dc.contributor.authorBekdemir, A.en_US
dc.contributor.authorAtilgan, A.en_US
dc.contributor.authorAkkaya, E. U.en_US
dc.date.accessioned2015-07-28T12:02:05Z
dc.date.available2015-07-28T12:02:05Z
dc.date.issued2014en_US
dc.departmentDepartment of Chemistryen_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.description.abstractPhotodynamic therapy (PDT), especially with the recent advances in photosensitizer (PS) design, has already been established as a noninvasive technique for cancer treatment. Recently, near-IR-based absorbing PSs that have a rising potency to implement light-triggered tumor ablation have attracted much attention since near-IR light in the 650-850 nm range penetrates more deeply in tissues. Up to now, numerous nanomaterials tailored to suitable sizes have been studied for effective delivery of PSs. In this study, four different types of Bodipy-based PSs were covalently attached to magnetic resonance imaging (MRI) active, biocompatible, and nontoxic nanocarriers and generation of singlet oxygen capabilities were evaluated. It was demonstrated that these core-shell nanoparticles are promising delivery vehicles of PSs for use in diagnosis and therapy.en_US
dc.identifier.doi10.1515/pac-2013-1114,en_US
dc.identifier.issn0033-4545
dc.identifier.urihttp://hdl.handle.net/11693/12591
dc.language.isoEnglishen_US
dc.publisherDe Gruyteren_US
dc.relation.isversionofhttp://dx.doi.org/10.1515/pac-2013-1114,en_US
dc.source.titlePure and Applied Chemistryen_US
dc.subjectBodipyen_US
dc.subjectCore-shell nanoparticlesen_US
dc.subjectIupac congress-44en_US
dc.subjectMagnetic resonance imagingen_US
dc.subjectPhotodynamic therapyen_US
dc.subjectPhotosensitizeren_US
dc.subjectSuperparamagnetic iron oxide nanoparticlesen_US
dc.titleNear IR absorbing bodipy-functionalized SPIONs: a potential magnetic nanoplatform for diagnosis and therapyen_US
dc.typeArticleen_US

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Department of Chemistry
Institute of Materials Science and Nanotechnology (UNAM)