Chromogenic and fluorogenic sensing of biological thiols in aqueous solutions using BODIPY-based reagents

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10.1021-ol303306s.pdf (1.21 MB)

Date

2013

Authors

Isik, M.
Ozdemir, T.
Turan, I. S.
Kolemen, S.
Akkaya, E. U.

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Source Title

Organic Letters

Print ISSN

1523-7060

Electronic ISSN

1523-7052

Publisher

American Chemical Society

Volume

15

Issue

1

Pages

216 - 219

Language

English

Type

Article

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Abstract

Judicious design of BODIPY dyes carrying nitroethenyl substituents in conjugation with the BODIPY core yields dyes that respond to biological thiols by both absorbance and emission changes. Incorporation of solubilizing ethyleneglycol units ensures water solubility. The result is bright signaling of biologically relevant thiols in the longer wavelength region of the visible spectrum and in aqueous solutions.

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Keywords

Fluorescent-probe, Energy-transfer, Efficient Photosensitizers, Photodynamic Therapy, Highly Efficient, Logic Gates, Dyes, Glutathione, Derivatives, Emission

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Permalink

http://hdl.handle.net/11693/11939

Published Version (Please cite this version)

http://dx.doi.org/10.1021/ol303306s

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Scholarly Publications - Chemistry
Scholarly Publications - UNAM