Chromogenic and fluorogenic sensing of biological thiols in aqueous solutions using BODIPY-based reagents

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10.1021-ol303306s.pdf (1.21 MB)

Date

2013

Authors

Isik, M.
Ozdemir, T.
Turan, I. S.
Kolemen, S.
Akkaya, E. U.

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Abstract

Judicious design of BODIPY dyes carrying nitroethenyl substituents in conjugation with the BODIPY core yields dyes that respond to biological thiols by both absorbance and emission changes. Incorporation of solubilizing ethyleneglycol units ensures water solubility. The result is bright signaling of biologically relevant thiols in the longer wavelength region of the visible spectrum and in aqueous solutions.

Source Title

Organic Letters

Publisher

American Chemical Society

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Keywords

Fluorescent-probe, Energy-transfer, Efficient Photosensitizers, Photodynamic Therapy, Highly Efficient, Logic Gates, Dyes, Glutathione, Derivatives, Emission

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http://hdl.handle.net/11693/11939

Published Version (Please cite this version)

http://dx.doi.org/10.1021/ol303306s

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Scholarly Publications - Chemistry
Scholarly Publications - UNAM

Language

English

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Article