Design of synthetic biological devices for detection and targeting human diseases

Date
2022-01-01
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Publisher
Elsevier
Volume
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Pages
251 - 269
Language
English
Type
Book Chapter
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Abstract

Interpreting signals coming from the surrounding environment and responding to these stimuli by adjusting physical or metabolic state is the most fundamental ability of living organisms. Repurposing these natural abilities for the detection and responding to different molecules is one of the key focuses of synthetic biology because the overall strategy could provide advanced solutions for different diseases. Also by being naturally suitable to the design-build-test-learn manner of synthetic biology, biosensors are great examples of what engineering and biology could achieve when they come together. Literature has many examples of intellectually designed biosensor systems, which may overachieve and outperform existing technologies with a completely biocompatible structure. In this chapter, design and application of these biosensor systems will be investigated.

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Book Title
New Frontiers and Applications of Synthetic Biology
Keywords
Biosensors, Cancer, Infectious diseases, Metabolic diseases, Synthetic biology, Toxicity
Citation
Published Version (Please cite this version)