Comparative evaluation of in vitro cytotoxic effects among parent abietyl alcohol and novel fatty acid ester derivatives against MCF7 and hepatocellular carcinoma cell lines

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buir.contributor.authorMustufa, Muhammad Ayaz
buir.contributor.authorÖzen, Çiğdem
buir.contributor.authorÖztürk, Mehmet
dc.citation.epage2018en_US
dc.citation.issueNumber6en_US
dc.citation.spage2013en_US
dc.citation.volumeNumber27en_US
dc.contributor.authorMustufa, Muhammad Ayazen_US
dc.contributor.authorAslam, A.en_US
dc.contributor.authorÖzen, Çiğdemen_US
dc.contributor.authorHashmi, I. A.en_US
dc.contributor.authorNaqvi, N.en_US
dc.contributor.authorÖztürk, Mehmeten_US
dc.contributor.authorAli, F. I.en_US
dc.date.accessioned2016-02-08T10:37:39Z
dc.date.available2016-02-08T10:37:39Z
dc.date.issued2014en_US
dc.departmentGenetics and Biotechnology Research Center (BİLGEN)en_US
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.description.abstractSynthesis of twelve hitherto unreported esters of abietyl alcohol and screening of these esters against four cancer cell lines including one breast cancer line MCF7 and four hepatocellular carcinoma cell lines (HCC) Huh7, Hep3B, Snu449 and Plc has been determined using SRB assay. The Cell cycle progression showed changes in cellular behaviour after 48 and 72 hours in MCF7 and Huh7 cell lines. Abietyl alcohol was obtained from the reduction of abietic acid, a tricyclic diterpene, isolated from oleoresin of Pinus longifolia Roxberghii.en_US
dc.identifier.issn1011-601X
dc.identifier.urihttp://hdl.handle.net/11693/25013
dc.language.isoEnglishen_US
dc.publisherPakistan Journal of Pharmaceutical Sciencesen_US
dc.source.titlePakistan Journal of Pharmaceutical Sciencesen_US
dc.subjectAbietic aciden_US
dc.subjectCancer cell linesen_US
dc.subjectDiterpeneen_US
dc.subjectSRB assayen_US
dc.subjectSteglich esterificationen_US
dc.titleComparative evaluation of in vitro cytotoxic effects among parent abietyl alcohol and novel fatty acid ester derivatives against MCF7 and hepatocellular carcinoma cell linesen_US
dc.typeArticleen_US

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