Biosensors for early disease diagnosis

Date
2016-03-11
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Publisher
John Wiley & Sons
Volume
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Pages
235 - 270
Language
English
Type
Book Chapter
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Abstract

This chapter focuses on biosensor types, their detection limits, analysis times, and the diseases they are suitable for detecting. In addition, as nanomaterials are an effective means of producing small‐scale diagnostic devices, nanostructures have been commonly employed in biosensor design. Consequently, a section is devoted to the types of nanomaterials currently under use in biosensor design. Biosensors can be classified according to their recognition element (e.g., enzymes, antibodies, nucleic acids), output type (e.g., optical, electrical, mechanical), detection principle (e.g., surface plasmon resonance (SPR) based, surface‐enhanced Raman spectroscopy (SERS) based, quartz crystal microbalance (QCM) based), or intended use (in vivo or ex vivo). These factors all play vital roles in determining the sensitivity and selectivity of a biosensor and are considered separately.

Course
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Book Title
Therapeutic Nanomaterials
Keywords
Biosensor design, Biosensor‐based disease detection, Early disease diagnosis, Nanomaterials, Nanotechnology, Small‐scale diagnostic devices
Citation