Functional subdomains within human FFA

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dc.citation.epage16766en_US
dc.citation.issueNumber42en_US
dc.citation.spage16748en_US
dc.citation.volumeNumber33en_US
dc.contributor.authorÇukur, T.en_US
dc.contributor.authorHuth, A. G.en_US
dc.contributor.authorNishimoto, S.en_US
dc.contributor.authorGallant, J. L.en_US
dc.date.accessioned2016-02-08T09:34:28Z
dc.date.available2016-02-08T09:34:28Z
dc.date.issued2013en_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.description.abstractThe fusiform face area (FFA) is a well-studied human brain region that shows strong activation for faces. In functional MRI studies, FFA is often assumed to be a homogeneous collection of voxels with similar visual tuning. To test this assumption, we used natural movies and a quantitative voxelwise modeling and decoding framework to estimate category tuning profiles for individual voxels within FFA. We find that the responses in most FFA voxels are strongly enhanced by faces, as reported in previous studies. However, we also find that responses of individual voxels are selectively enhanced or suppressed by a wide variety of other categories and that these broader tuning profiles differ across FFA voxels. Cluster analysis of category tuning profiles across voxels reveals three spatially segregated functional subdomains within FFA. These subdomains differ primarily in their responses for nonface categories, such as animals, vehicles, and communication verbs. Furthermore, this segregation does not depend on the statistical threshold used to define FFA from responses to functional localizers. These results suggest that voxels within FFA represent more diverse information about object and action categories than generally assumed. © 2013 the authors.en_US
dc.description.provenanceMade available in DSpace on 2016-02-08T09:34:28Z (GMT). No. of bitstreams: 1 bilkent-research-paper.pdf: 70227 bytes, checksum: 26e812c6f5156f83f0e77b261a471b5a (MD5) Previous issue date: 2013en
dc.identifier.doi10.1523/JNEUROSCI.1259-13.2013en_US
dc.identifier.issn0270-6474
dc.identifier.urihttp://hdl.handle.net/11693/20752
dc.language.isoEnglishen_US
dc.publisherSociety for Neuroscienceen_US
dc.relation.isversionofhttp://dx.doi.org/10.1523/JNEUROSCI.1259-13.2013en_US
dc.source.titleJournal of Neuroscienceen_US
dc.subjectAdulten_US
dc.subjectBrain Mappingen_US
dc.subjectFemaleen_US
dc.subjectFunctional Neuroimagingen_US
dc.subjectHumansen_US
dc.subjectImage Processing, Computer-Assisteden_US
dc.subjectMagnetic Resonance Imagingen_US
dc.subjectMaleen_US
dc.subjectOccipital Lobeen_US
dc.subjectPattern Recognition, Visualen_US
dc.subjectPhotic Stimulationen_US
dc.subjectTemporal Lobeen_US
dc.subjectVisual Perceptionen_US
dc.titleFunctional subdomains within human FFAen_US
dc.typeArticleen_US

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