Air-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgery

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dc.citation.epage101104-4en_US
dc.citation.issueNumber10en_US
dc.citation.spage101104-1en_US
dc.citation.volumeNumber100en_US
dc.contributor.authorLanin, A.en_US
dc.contributor.authorFedotov, I. V.en_US
dc.contributor.authorSidorov Biryukov, D. S.en_US
dc.contributor.authorDoronina Amitonova, L. V.en_US
dc.contributor.authorIvashkina, O. I.en_US
dc.contributor.authorZots, M. A.en_US
dc.contributor.authorSun, C. K.en_US
dc.contributor.authorIlday, F. O.en_US
dc.contributor.authorFedotov, A. B.en_US
dc.contributor.authorAnokhin, K. V.en_US
dc.contributor.authorZheltikov, A. M.en_US
dc.date.accessioned2015-07-28T12:05:13Z
dc.date.available2015-07-28T12:05:13Z
dc.date.issued2012-03-06en_US
dc.departmentDepartment of Physicsen_US
dc.description.abstractLarge-core hollow photonic- crystal fibers (PCFs) are shown to enable a fiber-format air-guided delivery of ultrashort infrared laser pulses for neurosurgery and nonlinear-optical imaging. With an appropriate dispersion precompensation, an anomalously dispersive 15-mu m-core hollow PCF compresses 510-fs, 1070-nm light pulses to a pulse width of about 110 fs, providing a peak power in excess of 5 MW. The compressed PCF output is employed to induce a local photodisruption of corpus callosum tissues in mouse brain and is used to generate the third harmonic in brain tissues, which is captured by the PCF and delivered to a detector through the PCF cladding.en_US
dc.description.provenanceMade available in DSpace on 2015-07-28T12:05:13Z (GMT). No. of bitstreams: 1 10.1063-1.3681777.pdf: 1211429 bytes, checksum: f8c3d93519b745ee923761e905f754b2 (MD5)en
dc.identifier.doi10.1063/1.3681777en_US
dc.identifier.issn0003-6951
dc.identifier.urihttp://hdl.handle.net/11693/13222
dc.language.isoEnglishen_US
dc.publisherAIP Publishing LLCen_US
dc.relation.isversionofhttp://dx.doi.org/10.1063/1.3681777en_US
dc.source.titleApplied Physics Lettersen_US
dc.subjectPicosecond pulsesen_US
dc.subjectSoliton outputen_US
dc.subjectMicroscopyen_US
dc.subjectBreakdownen_US
dc.titleAir-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgeryen_US
dc.typeArticleen_US

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