Permittivity-based classification by the integration of impedance cytometry and microwave sensing

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Abstract

The direct determination of the permittivity of individual micro-objects has proven challenging due to the convoluting effect of their geometric size on capacitive signals (i.e., on the electric size of a particle). To overcome this challenge, we have developed a sensing platform to independently obtain both the geometric and electric size of organic and inorganic particles, by combining impedance cytometry and microwave resonant sensing in a microfluidic chip. This way the microwave signal is normalized to yield an intrinsic parameter that depends only on permittivity. The permittivity can then be used for material classification or single-cell interrogation.

Source Title

2023 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)

Publisher

IEEE - Institute of Electrical and Electronics Engineers

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Citation

Published Version (Please cite this version)

Language

English