Permittivity-based classification by the integration of impedance cytometry and microwave sensing
Date
2023-11-07
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Source Title
2023 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)
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Publisher
IEEE - Institute of Electrical and Electronics Engineers
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Pages
1 - 3
Language
English
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Abstract
The direct determination of the permittivity of individual micro-objects has proven challenging due to the convoluting effect of their geometric size on capacitive signals (i.e., on the electric size of a particle). To overcome this challenge, we have developed a sensing platform to independently obtain both the geometric and electric size of organic and inorganic particles, by combining impedance cytometry and microwave resonant sensing in a microfluidic chip. This way the microwave signal is normalized to yield an intrinsic parameter that depends only on permittivity. The permittivity can then be used for material classification or single-cell interrogation.