Surface enhanced Raman spectroscopy of unilamellar liposomes loaded with silver nanoparticles

dc.citation.epage8900en_US
dc.citation.issueNumber12en_US
dc.citation.spage8894en_US
dc.citation.volumeNumber17en_US
dc.contributor.authorToren, P.en_US
dc.contributor.authorTekinay, T.en_US
dc.contributor.authorAyas S.en_US
dc.contributor.authorDana, A.en_US
dc.contributor.authorTunc, I.en_US
dc.date.accessioned2019-02-25T09:06:24Z
dc.date.available2019-02-25T09:06:24Z
dc.date.issued2017en_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.description.abstractImaging organic molecules using surface-enhanced Raman spectroscopy (SERS) has drawn attention due to its non-invasive nature and label-free approach. The SERS approach can be used in tracking organic molecules and monitoring unique Raman spectra of the organic molecules bound to metal nanoparticles (NPs). We prepared unilamellar liposomes composed of 1,2-dipalmitoylsn-glycero-3-phosphocholine (DPPC) molecules with a diameter of around 100 nm. Electrostatic binding of silver (Ag) NPs on the surface of the unilamellar liposomes was achieved by the reduction of silver nitrate (AgNO3) which produces SERS active silver colloidal particles on the unilamellar liposome surfaces. Highly enhanced electromagnetic fields localized around neighbouring Ag NPs provide hot-spot construction around the liposomes, due to the spatial distribution of SERS enhancement in the unilamellar liposomes. It was observed that the signals fluctuate on a second time scale, presumably due to conformational change of DPPC chain and local Brownian motion of liposomal spheres.en_US
dc.description.provenanceSubmitted by Zeynep Aykut (zeynepay@bilkent.edu.tr) on 2019-02-25T09:06:24Z No. of bitstreams: 1 Surface_enhanced_Raman_spectroscopy_of_unilamellar_liposomes_loaded_with_silver_nanoparticles.pdf: 8514849 bytes, checksum: 37c8cf432cf889985718cb2d238fed4f (MD5)en
dc.description.provenanceMade available in DSpace on 2019-02-25T09:06:24Z (GMT). No. of bitstreams: 1 Surface_enhanced_Raman_spectroscopy_of_unilamellar_liposomes_loaded_with_silver_nanoparticles.pdf: 8514849 bytes, checksum: 37c8cf432cf889985718cb2d238fed4f (MD5) Previous issue date: 2017en
dc.identifier.doi10.1166/jnn.2017.13880en_US
dc.identifier.eissn1533-4899en_US
dc.identifier.issn1533-4880en_US
dc.identifier.urihttp://hdl.handle.net/11693/50601
dc.language.isoEnglishen_US
dc.publisherAmerican Scientific Publishersen_US
dc.relation.isversionofhttps://doi.org/10.1166/jnn.2017.13880en_US
dc.source.titleJournal of Nanoscience and Nanotechnologyen_US
dc.subjectSurface-Enhanced Raman Spectroscopy (SERS)en_US
dc.subjectHot-spotsen_US
dc.subjectSilver nanoparticlesen_US
dc.subjectLiposomesen_US
dc.subjectULVsen_US
dc.titleSurface enhanced Raman spectroscopy of unilamellar liposomes loaded with silver nanoparticlesen_US
dc.typeArticleen_US
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