Real-time impedimetric droplet measurement (iDM)

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buir.contributor.authorSaateh, Abtin
buir.contributor.authorKalantarifard, Ali
buir.contributor.authorÇelik, Oğuz Tolga
buir.contributor.authorAsghari, Mohammad
buir.contributor.authorSerhatlıoğlu, Murat
buir.contributor.authorElbüken, Çağlar
dc.citation.epage3824en_US
dc.citation.issueNumber22en_US
dc.citation.spage3815en_US
dc.citation.volumeNumber19en_US
dc.contributor.authorSaateh, Abtinen_US
dc.contributor.authorKalantarifard, Alien_US
dc.contributor.authorÇelik, Oğuz Tolgaen_US
dc.contributor.authorAsghari, Mohammaden_US
dc.contributor.authorSerhatlıoğlu, Muraten_US
dc.contributor.authorElbüken, Çağlaren_US
dc.date.accessioned2020-02-17T11:18:05Zen_US
dc.date.available2020-02-17T11:18:05Zen_US
dc.date.issued2019en_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.departmentNanotechnology Research Center (NANOTAM)en_US
dc.description.abstractDroplet-based microfluidic systems require a precise control of droplet physical properties; hence, measuring the morphological properties of droplets is critical to obtain high sensitivity analysis. The ability to perform such measurements in real-time is another demand which has not been addressed yet. In this study, we used coplanar electrodes configured in the differential measurement mode for impedimetric measurement of size and velocity. To obtain the size of the droplets, detailed 3D finite element simulations of the system were performed. The interaction of the non-uniform electric field and the droplet was investigated. Electrode geometry optimization steps were described and design guideline rules were laid out. User-friendly software was developed for real-time observation of droplet length and velocity together with in situ statistical analysis results. A comparison between impedimetric and optical measurement tools is given. Finally, to illustrate the benefit of having real-time analysis, iDM was used to synthesize particles with a predefined monodispersity limit and to study the response times of syringe pump and pressure pump driven droplet generation devices. This analysis allows one to evaluate the ‘warm-up’ time for a droplet generator system, after which droplets reach the desired steady-state size required by the application of interest.en_US
dc.identifier.doi10.1039/c9lc00641aen_US
dc.identifier.eissn1473-0189
dc.identifier.urihttp://hdl.handle.net/11693/53392
dc.language.isoEnglishen_US
dc.publisherRoyal Society of Chemistryen_US
dc.relation.isversionofhttps://dx.doi.org/10.1039/c9lc00641aen_US
dc.source.titleLab on a Chipen_US
dc.titleReal-time impedimetric droplet measurement (iDM)en_US
dc.typeArticleen_US

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Institute of Materials Science and Nanotechnology (UNAM)
Nanotechnology Research Center (NANOTAM)