Cytotoxic and bioactive properties of different color tulip flowers and degradation kinetic of tulip flower anthocyanins

Date
2013
Authors
Sagdic, O.
Ekici, L.
Ozturk, I.
Tekinay, T.
Polat, B.
Tastemur, B.
Bayram, O.
Senturk, B.
Advisor
Instructor
Source Title
Food and Chemical Toxicology
Print ISSN
0278-6915
Electronic ISSN
Publisher
Pergamon Press
Volume
58
Issue
Pages
432 - 439
Language
English
Type
Article
Journal Title
Journal ISSN
Volume Title
Abstract

This study was conducted to determine the potential use of anthocyanin-based extracts (ABEs) of wasted tulip flowers as food/drug colorants. For this aim, wasted tulip flowers were samples and analyzed for their bioactive properties and cytotoxicity. Total phenolic contents of the extracts of the claret red (126.55. mg of gallic acid equivalent (GAE)/g dry extract) and orange-red (113.76. mg GAE/g dry extract) flowers were the higher than those of the other tulip flowers. Total anthocyanin levels of the violet, orange-red, claret red and pink tulip flower extracts were determined as 265.04, 236.49, 839.08 and 404.45. mg pelargonidin 3-glucoside/kg dry extract, respectively and these levels were higher than those of the other flowers. The extracts were more effective for the inhibition of Listeria monocytogenes, Staphylococcus aureus and Yersinia enterocolitica compared to other tested bacteria. Additionally, the cytotoxic effects of five different tulip flower extracts on human breast adenocarcinoma (MCF-7) cell line were investigated. The results showed that the orange red, pink and violet extracts had no cytotoxic activity against MCF-7 cell lines while yellow and claret red extracts appeared to be toxic for the cells. Overall, the extracts of tulip flowers with different colors possess remarkable bioactive and cytotoxic properties. © 2013 Elsevier Ltd.

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Other identifiers
Book Title
Keywords
Bioactivity, Cytotoxicity, Kinetic, Wasted tulip flowers, Alcohol, Anthocyanin, Antiinfective agent, Antioxidant, Phenol derivative, Plant extract, Tulipa gesneriana extract, Unclassified drug, Water, Antibacterial activity, Antioxidant activity, Bacterial growth, Biological activity, Cell strain MCF 7, Cell survival, Cell viability, Controlled study, Cytotoxicity, Cytotoxicity test, Degradation kinetics, Drug determination, Flower, Ggrowth inhibition, Human, Human cell, Listeria monocytogenes, Nonhuman, Staphylococcus aureus, Survival rate, Thermostability
Citation
Published Version (Please cite this version)