Design and construction of protein and peptide-based self-assembled nanostructures

Date
2022-01-01
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Publisher
Elsevier
Volume
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Pages
193 - 204
Language
English
Type
Book Chapter
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Abstract

Self-assembly is the driving force for the formation of biological materials. From nucleic acid conformations to more complex cellular organizations, self-assembling structures shape biological functionality. So, the design of self-assembling biomolecular structures holds a great advantage for enhanced material properties. In biological processes, inorganic structures are created in a hierarchical fashion utilizing biomolecule-based templates. Since they have recognition and self-assembly properties, biomolecules can control highly organized inorganic material formation in nature. The bio-templating approach takes advantage of biomolecules’ self-assembly properties to develop new nanostructures with superior chemical and physical properties. Here, peptides and proteins including β-sheets, β-hairpins, α-helix, amyloid, capsid, ferritin, and albumin, used in the formation of nanostructures with desired functionality under mild environmental conditions, and their applications are discussed.

Course
Other identifiers
Book Title
Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine
Keywords
Bio-template, Nanofabrication, Nanoplatforms, Peptide, Protein, Self-assembly
Citation
Published Version (Please cite this version)