Encapsulation of vanillin/cyclodextrin inclusion complex in electrospun polyvinyl alcohol (PVA) nanowebs: prolonged shelf-life and high temperature stability of vanillin

Date
2012-08
Advisor
Instructor
Source Title
Food Chemistry
Print ISSN
0308-8146
Electronic ISSN
Publisher
Volume
133
Issue
3
Pages
641 - 649
Language
English
Type
Article
Journal Title
Journal ISSN
Volume Title
Abstract

We produced functional nanowebs, containing vanillin, having prolonged shelf-life and high temperature stability facilitated by cyclodextrin (CD) inclusion complexation. Polyvinyl alcohol (PVA) nanowebs incorporating vanillin/cyclodextrin inclusion complex (vanillin/CD-IC) were produced via electrospinning technique. The vanillin/CD-IC was prepared with three types of CDs; α-CD, β-CD and γ-CD to find out the most favourable CD type for the stabilization of vanillin. PVA/vanillin/CD-IC nanofibres, having fibre diameters around ∼200 nm, were successfully electrospun from aqueous mixture of PVA and vanillin/CD-IC. Our results indicated that vanillin with enhanced durability and high temperature stability was achieved for PVA/vanillin/CD-IC nanowebs due to complexation of vanillin with CD, whereas the PVA nanofibres without CD-IC could not effectively preserve the vanillin. Additionally, we observed that PVA/vanillin/γ-CD-IC nanoweb was more effective for the stabilization and slow release of vanillin suggesting that the strength of interaction between vanillin and the γ-CD cavity is stronger when compared to α-CD and β-CD. © 2012 Elsevier Ltd. All rights reserved.

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Keywords
Cyclodextrin, Electrospinning, Inclusion complex, Nanofibre, Polyvinyl alcohol (PVA), Vanillin, Aqueous mixtures, CdS, Electrospinning techniques, Electrospuns, High temperature stability, Inclusion complex, Inclusion complexation, Nanoweb, Polyvinyl alcohol (PVA), Shelf life, Slow release, Vanillin, Cyclodextrins, Electrospinning, Nanofibers, Polyvinyl alcohols, Stabilization, Nanostructures, Alpha cyclodextrin, Beta cyclodextrin, Cyclodextrin, Gamma cyclodextrin, Nanomaterial, Nanoweb, Polyvinyl alcohol, Unclassified drug, Vanillin, Article, Electrospinning, Encapsulation, Shelf life, Thermostability
Citation
Published Version (Please cite this version)