Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases

Simple item page
dc.citation.epage8en_US
dc.citation.issueNumber4en_US
dc.citation.spage1en_US
dc.citation.volumeNumber11en_US
dc.contributor.authorChabchoub, G.en_US
dc.contributor.authorUz, E.en_US
dc.contributor.authorMaalej, A.en_US
dc.contributor.authorMustafa, C. A.en_US
dc.contributor.authorRebai, A.en_US
dc.contributor.authorMnif, M.en_US
dc.contributor.authorBahloul, Z.en_US
dc.contributor.authorFarid, N. R.en_US
dc.contributor.authorOzcelik, T.en_US
dc.contributor.authorAyadi, H.en_US
dc.date.accessioned2016-02-08T10:03:34Z
dc.date.available2016-02-08T10:03:34Z
dc.date.issued2009en_US
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.departmentNanotechnology Research Center (NANOTAM)en_US
dc.description.abstractIntroduction The majority of autoimmune diseases such as rheumatoid arthritis (RA) and autoimmune thyroid diseases (AITDs) are characterized by a striking female predominance superimposed on a predisposing genetic background. The role of extremely skewed X-chromosome inactivation (XCI) has been questioned in the pathogenesis of several autoimmune diseases.en_US
dc.description.provenanceMade available in DSpace on 2016-02-08T10:03:34Z (GMT). No. of bitstreams: 1 bilkent-research-paper.pdf: 70227 bytes, checksum: 26e812c6f5156f83f0e77b261a471b5a (MD5) Previous issue date: 2009en
dc.identifier.doi10.1186/ar2759en_US
dc.identifier.issn1478-6362
dc.identifier.urihttp://hdl.handle.net/11693/22696
dc.language.isoEnglishen_US
dc.publisherBioMed Centralen_US
dc.relation.isversionofhttp://dx.doi.org/10.1186/ar2759en_US
dc.source.titleArthritis Research and Therapyen_US
dc.subjectAndrogen receptoren_US
dc.subjectCyclic citrullinated peptide antibodyen_US
dc.subjectHydroxychloroquineen_US
dc.subjectMethotrexateen_US
dc.subjectPenicillamineen_US
dc.subjectRheumatoid factoren_US
dc.subjectAutoantibodyen_US
dc.subjectAlleleen_US
dc.subjectAutoimmune thyroiditisen_US
dc.subjectChromosome analysisen_US
dc.subjectControlled studyen_US
dc.subjectFemaleen_US
dc.subjectGenetic associationen_US
dc.subjectGenetic predispositionen_US
dc.subjectHumanen_US
dc.subjectImmunosuppressive treatmenten_US
dc.subjectMajor clinical studyen_US
dc.subjectPhenotypeen_US
dc.subjectPolymerase chain reactionen_US
dc.subjectX chromosome inactivationen_US
dc.subjectAutoimmune diseaseen_US
dc.subjectBlooden_US
dc.subjectEnzyme linked immunosorbent assayen_US
dc.subjectGeneticsen_US
dc.subjectMiddle ageden_US
dc.subjectRheumatoid arthritisen_US
dc.subjectThyroid diseaseen_US
dc.subjectX chromosomeen_US
dc.subjectAdulten_US
dc.subjectArthritis, Rheumatoiden_US
dc.subjectAutoantibodiesen_US
dc.subjectAutoimmune Diseasesen_US
dc.subjectChromosomes, Human, Xen_US
dc.subjectEnzyme-Linked Immunosorbent Assayen_US
dc.subjectFluorescent Antibody Techniqueen_US
dc.subjectGenetic Predisposition to Diseaseen_US
dc.subjectHumansen_US
dc.subjectPolymerase Chain Reactionen_US
dc.subjectThyroid Diseasesen_US
dc.subjectTunisiaen_US
dc.titleAnalysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseasesen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases.pdf
Size:
365.54 KB
Format:
Adobe Portable Document Format
Description:
Full printable version
Download

Collections

Scholarly Publications - Molecular Biology and Genetics
Scholarly Publications - NANOTAM