Tape'n roll inertial microfluidics

Limited Access
This item is unavailable until:
2021-11-01
Date
2019
Editor(s)
Advisor
Supervisor
Co-Advisor
Co-Supervisor
Instructor
Source Title
Sensors and Actuators A: Physical
Print ISSN
0924-4247
Electronic ISSN
Publisher
Elsevier
Volume
299
Issue
Pages
111630-1 - 111630-9
Language
English
Journal Title
Journal ISSN
Volume Title
Series
Abstract

Particle focusing and separation in microfluidic devices are critical for biological and medical applications. Inertial microfluidics is used for high throughput bio-particle focusing and separation. Most of the inertial microfluidic systems use planar structures for squeezing the particles in streams. Particle manipulation in 3D structures is often overlooked due to the complexity of the fabrication. In this study, we introduce some novel microchannel designs for inertial microfluidics by using a simple fabrication method that allows construction of both 2D and 3D structures. First, inertial migration of particles in 2D layouts including straight, spiral, and square spiral channels is investigated. Afterward, by applying a “tape’n roll” method, helical and double oriented spiral channels are configured and unexplored inertial migration behaviours are observed. Thanks to the simplicity of the fabrication and the unique characteristics of the new designs, high performance microfluidic inertial migration results can be obtained without any need for complicated microfabrication steps. The design optimization cycle can also be shortened using a computational approach we introduce in this study.

Course
Other identifiers
Book Title
Citation
Published Version (Please cite this version)