Noncovalent functionalization of a nanofibrous network with a bio-inspired heavy metal binding peptide
Date
2013
Editor(s)
Advisor
Supervisor
Co-Advisor
Co-Supervisor
Instructor
Source Title
RSC Advances
Print ISSN
2045-547X
Electronic ISSN
2046-2069
Publisher
Volume
3
Issue
46
Pages
24215 - 24221
Language
English
Type
Journal Title
Journal ISSN
Volume Title
Series
Abstract
Peptide-polymer nanofibrous networks can be developed to obtain hybrid systems providing both functionalities of peptides and stability and processability of the polymers. In this work, a bio-inspired heavy metal binding peptide was synthesized and noncovalently immobilized on water-insoluble electrospun hydroxypropyl-beta-cyclodextrin nanofibers (CDNF). The peptide functionalized hybrid nanofibers were able to bind to heavy metal ions and facilitated removal of metal ions from water. The peptide-polymer scavenging system has potential for development of further molecular recognition systems with various peptide sequences or host-guest inclusion complexes. © 2013 The Royal Society of Chemistry.