Singlet oxygen generation with chemical excitation of an erythrosine-luminol conjugate

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dc.citation.epage1371en_US
dc.citation.issueNumber4en_US
dc.citation.spage1367en_US
dc.citation.volumeNumber2en_US
dc.contributor.authorYesilgul, N.en_US
dc.contributor.authorUyar, T. B.en_US
dc.contributor.authorSeven, O.en_US
dc.contributor.authorAkkaya, E. U.en_US
dc.date.accessioned2018-04-12T11:08:26Z
dc.date.available2018-04-12T11:08:26Z
dc.date.issued2017en_US
dc.departmentDepartment of Chemistryen_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.description.abstractChemical generation of singlet oxygen under biologically relevant conditions is very important, considering the role played by singlet oxygen in cancer therapeutics. We now demonstrate that a luminol derivative can be chemically excited and transfer the excitation energy to the covalently attached photosensitizer derived from erythrosin. A photosensitizer module, when excited in this manner, can generate singlet oxygen in solution. As hydrogen peroxide is present in a relatively high concentration in cancer cells, singlet oxygen generation through chemical excitation may evolve into an important therapeutic approach.en_US
dc.identifier.doi10.1021/acsomega.7b00228en_US
dc.identifier.issn2470-1343
dc.identifier.urihttp://hdl.handle.net/11693/37279
dc.language.isoEnglishen_US
dc.publisherAmerican Chemical Societyen_US
dc.relation.isversionofhttp://dx.doi.org/10.1021/acsomega.7b00228en_US
dc.source.titleACS Omegaen_US
dc.titleSinglet oxygen generation with chemical excitation of an erythrosine-luminol conjugateen_US
dc.typeArticleen_US

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