PEGylated calix[4]arene as a carrier for a Bodipy-based photosensitizer

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dc.citation.epage540en_US
dc.citation.issueNumber2en_US
dc.citation.spage538en_US
dc.citation.volumeNumber55en_US
dc.contributor.authorCakmak, Y.en_US
dc.contributor.authorNalbantoglu, T.en_US
dc.contributor.authorDurgut, T.en_US
dc.contributor.authorAkkaya, E. U.en_US
dc.date.accessioned2016-02-08T10:58:55Z
dc.date.available2016-02-08T10:58:55Z
dc.date.issued2014en_US
dc.departmentDepartment of Chemistryen_US
dc.description.abstractHeavy atom substituted Bodipy compounds, unlike the parent chromophore, undergo rapid intersystem crossing to generate singlet oxygen, which is the primary cytotoxic agent exploited in PDT. In this work, we show that an organic soluble calix[4]arene can be functionalized by Knoevenagel reaction and then converted into an amphiphilic photosensitizer in a few steps. In addition to generating a potentially useful photosensitizer, the sequence of reactions is the first use of a Bodipy dye as a chromophoric/fluorogenic label without the typical reactive functional groups.en_US
dc.identifier.doi10.1016/j.tetlet.2013.11.083en_US
dc.identifier.eissn1873-3581
dc.identifier.issn0040-4039
dc.identifier.urihttp://hdl.handle.net/11693/26370
dc.language.isoEnglishen_US
dc.publisherElsevieren_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.tetlet.2013.11.083en_US
dc.source.titleTetrahedron Lettersen_US
dc.subjectBodipyen_US
dc.subjectCalixarenesen_US
dc.subjectPDTen_US
dc.subjectPhotosensitizersen_US
dc.subjectSinglet oxygenen_US
dc.titlePEGylated calix[4]arene as a carrier for a Bodipy-based photosensitizeren_US
dc.typeArticleen_US

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