Browsing by Subject "purine"
Now showing 1 - 1 of 1
- Results Per Page
- Sort Options
Item Open Access Synthesis of novel substituted purine derivatives and identification of the cell death mechanism(Elsevier Masson SAS, 2015) Demir, Z.; Guven, E.B.; Ozbey, S.; Kazak, C.; Atalay, R.C.; Tuncbilek, M.Novel substituted adenine and purine derivatives were designed and synthesized.Compound 36 displayed the greatest cytotoxic activity with IC50 less than 1 1/4M.36 induces senescence associated cell death, which was demonstrated with SA2-Gal assay. © 2014 Elsevier Masson SAS.