Browsing by Subject "LSPR"

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    Developing a transducer based on localized surface plasmon resonance (LSPR) of gold nanostructures for nanobiosensor applications
    (Trans Tech Publications, 2013) Turhan, Adil Burak; Ataman, D.; Çakmakyapan, S.; Mutlu, M.; Özbay, Ekmel; Vlachos, D. S.; Hristoforou, E.
    In this work, we report the nanofabrication, optical characterization, and electromagnetic modeling of various nanostructure arrays for localized surface plasmon resonance (LSPR) based biosensing studies. Comparison of the experimental results and simulation outputs of various nanostructure arrays was made and a good correspondence was achieved.
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    Functional gold nanoparticle coated surfaces for CA 125 cancer biomarker detection
    (TÜBİTAK, 2015) Tunç, İ.; Susapto, Hepi Hari; Güler, Mustafa Özgür
    Here we describe the detailed characterization of gold nanoparticle (Au Np) functionalized surfaces as a biosensing platform by studying a model streptavidin (SA)–biotin interaction. Conjugation of SA on Au Np immobilized on silicon (Si) and quartz surfaces and its interaction with biotin were characterized by X-ray photoelectron spectroscopy (XPS), UV-Vis spectroscopy, circular dichromism (CD) spectroscopy, and contact angle measurements. The immobilization method and atomic concentrations of Si 2p, Au 4f, S 2p, C 1s, N 1s, and O 1s of the resulting SA–biotin modified Si surface were determined by XPS. The CD spectrum and confocal microscopy imaging confirmed that step-by-step modification and bioconjugation can be monitored successfully. Such detailed and well-defined step-by-step characterization provides good information about the surface properties of biosensor platforms. In addition, the LSPR sensing ability of the Au Np based platforms was studied by using a model SA–biotin system. A 20 nm spectral red shift was detected when 150 nM SA was immobilized on to the Au Nps surface using the direct incubation/binding method on to the dry surface instead of the flow-injection method. The same platforms were also used to detect the CA 125 antibody–antigen system. Large spectral red shifts are very promising in terms of using these surfaces as LSPR biosensors
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    ItemOpen Access
    Plasmonic nanoparticle based nanobiosensors and nanophotodetectors
    (SPIE, 2013) Cinel, N.A.; Bütün, S.; Özbay, Ekmel
    Plasmonics mainly deals with light-matter interactions in metallic nanostructures. It has gathered interest since its discovery due to the benefits it provides when compared with photonics and electronics. It owes its popularity to the tremendous number of applications it serves for. In this paper, we review how plasmonic nanoparticles can be utilized in applications such as localized surface plasmon resonance based biosensing and enhancing performance of photodetectors. © 2013 SPIE.
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    ItemOpen Access
    Plasmonic nanoparticle based nanobiosensors and nanophotodetectors
    (SPIE, 2013) Cinel, Neval A.; Bütün, S.; Özbay, Ekmel
    Plasmonics mainly deals with light-matter interactions in metallic nanostructures. It has gathered interest since its discovery due to the benefits it provides when compared with photonics and electronics. It owes its popularity to the tremendous number of applications it serves for. In this paper, we review how plasmonic nanoparticles can be utilized in applications such as localized surface plasmon resonance based biosensing and enhancing performance of photodetectors. © 2013 SPIE.
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    SILVER nano-cylinders designed by EBL used as label free LSPR nano-biosensors
    (SPIE, 2011) Cinel, Neval A.; Bütün, Serkan; Özbay, Ekmel
    Localized Surface Plasmon Resonance (LSPR) is based on the electromagnetic-field enhancement of metallic nano-particles. It is observed at the metal-dielectric interface and the resonance wavelength can be tuned by the size, shape, and periodicity of the metallic nanoparticles and the surrounding dielectric environment. This makes LSPR a powerful candidate in bio-sensing. In the present work, the size and period dependency of the LSPR wavelength was studied through simulations and fabrications. The surface functionalization, that transforms the surface into a sensing platform was done and verified. Finally, the concentration dependency of the LSPR shifts was observed. All the measurements were done by a transmission set-up. The study is at an early stage, however results are promising. The detection of specific bacteria species can be made possible with such a detection method. © 2011 SPIE.