Browsing by Subject "Infectious diseases"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Item Open Access Combating infectious diseases with synthetic biology(American Chemical Society, 2022-01-25) Khan, Anooshay; Ostaku, Julian; Aras, Ebru; Safak Seker, Urartu OzgurOver the past decades, there have been numerous outbreaks, including parasitic, fungal, bacterial, and viral infections, worldwide. The rate at which infectious diseases are emerging is disproportionate to the rate of development for new strategies that could combat them. Therefore, there is an increasing demand to develop novel, specific, sensitive, and effective methods for infectious disease diagnosis and treatment. Designed synthetic systems and devices are becoming powerful tools to treat human diseases. The advancement in synthetic biology offers efficient, accurate, and cost-effective platforms for detecting and preventing infectious diseases. Herein we focus on the latest state of living theranostics and its implications.Item Open Access Design of synthetic biological devices for detection and targeting human diseases(Elsevier, 2022-01-01) Hacıosmanoğlu, Nedim; Köse, Sıla; Ostaku, Julian; Köksaldi, İlkay Çisil; Saltepe, Behide; Şeker, Urartu Özgür Şafak; Singh, V.Interpreting signals coming from the surrounding environment and responding to these stimuli by adjusting physical or metabolic state is the most fundamental ability of living organisms. Repurposing these natural abilities for the detection and responding to different molecules is one of the key focuses of synthetic biology because the overall strategy could provide advanced solutions for different diseases. Also by being naturally suitable to the design-build-test-learn manner of synthetic biology, biosensors are great examples of what engineering and biology could achieve when they come together. Literature has many examples of intellectually designed biosensor systems, which may overachieve and outperform existing technologies with a completely biocompatible structure. In this chapter, design and application of these biosensor systems will be investigated.