Browsing by Author "Balusamy, Brabu"

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Open Access
Electrospinning: A versatile processing technology for producing nanofibrous materials for biomedical and tissue-engineering applications
(Elsevier, 2017) Senthamizhan, Anitha; Balusamy, Brabu; Uyar, Tamer; Uyar, Tamer; Kny, E.
Electrospinning technique has been extensively acknowledged as an efficient and convenient approach for producing functional nanofibrous biomaterials. The performance of the electrospun nanofibers and their nanofibrous membrane can be improved by modifying/combining with active molecules in different ways. The topography and orientation of the fibrous assembly are effectively controlled by modifying the electrospinning setup. Despite the promising characteristics of nanofibers, insufficient mechanical properties, hydrophobic nature, ineffective pore-structure controllability, shrinkage, and distortion are identified as some limitations. Yet, recent studies have been devoted/combined with other approaches to overcome these disadvantages. This chapter summarizes the recent strategies employed to develop advanced electrospun nanofibrous membranes for biomedical and tissue-engineering applications.
Open Access
Electrospun nanofibrous materials for wound healing applications
(Elsevier, 2017) Balusamy, Brabu; Senthamizhan, Anitha; Uyar, Tamer; Uyar, Tamer; Kny, E.
Open Access
General strategy for fabrication of ordered one dimensional inorganic structures by electrospinning: structural evolution from belt to solid via hollow tubes
(Wiley-VCH Verlag GmbH & Co. KGaA, 2020-12-23) Senthamizhan, Anitha; Balusamy, Brabu; Çelebioğlu, Aslı; Uyar, T.
Super-structured hollow materials are the subject of intense research due to their attracting properties and diverse applications. Despite their significance, it still remains a crucial challenge to develop a simple and well-organized method to prepare the hollow tubes with controlled architectures. Herein, a general route to prepare structurally well-defined 1D zinc oxide (ZnO) structures by a single-spinneret electrospinning method coupled with thermal treatment is demonstrated for the first time and subsequently designated to identify high-performance materials for catalytic application. Two critical factors including tailoring the precursor amount and colloidal-stability of the precursor play critical role in tuning the structure precisely. The careful optimization of processing conditions enables chronological structural evolution from tubular to solid fiber structures composed of nanograins. These ZnO complex hollow structures showcase excellent photocatalytic performance; single nanograined wall hollow tubes manifest the high-catalytic performance over other samples with remarkable cycling stability. Benefitting from fabrication adaptability, different types of metal oxide hollow tubes are prepared that indicates the generality of the method. The proposed method postulates new insights for the development of electrospun hollow-structured fibers in a simple, cost-effective, and industrially feasible manner which holds apparent potential in many sectors.
Open Access
In vivo safety evaluations of electrospun nanofibers for biomedical applications
(Elsevier, 2017) Balusamy, Brabu; Senthamizhan, Anitha; Uyar, Tamer; Uyar, Tamer; Kny, E.
Open Access
Single nozzle electrospinning promoted hierarchical shell wall structured zinc oxide hollow tubes for water remediation
(Elsevier, 2021-03-09) Balusamy, Brabu; Senthamizhan, Anitha; Çelebioğlu, Aslı; Uyar, Tamer
Hypothesis Electrospun metal oxide hollow tubes are of great interest owing to their unique structural advantages compared to solid nanofibers. Although intensive research on preparation of hollow tubes have been devoted, formation of hierarchical shells remains a significant challenge. Experiments Herein, we demonstrate the fabrication of highly uniform, reproducible and industrially feasible ZnO hollow tubes (ZHT) with two-level hierarchical shells via a simple and versatile single-nozzle electrospinning strategy coupled with subsequent controlled thermal treatment. Findings The morphological investigation reveals that the hollow tubes built from nanostructures which has unique surface structure on their wall. The mechanism by which the composite fibers transferred to hollow tubes is primarily based on the evaporation rate of the polymeric template. Notably, tuning the heating rate from 5 °C to 50 °C/min possess adverse effect on formation of hollow tubes, thus subsequently produced ZnO nanoplates (ZNP). The comparative photocatalytic analysis emphasized that ZHT shows higher photocatalytic activity than ZNP. This finding has made an evident that the inherent abundant defects in the electrospun derived nanostructures are not only sufficient for improving the photocatalytic activity. Studies on bacterial growth inhibition showcased a superior bactericidal effect against Staphylococcus aureus and Escherichia coli implying its potentiality for disinfecting the bacteria from water.