Electrostatics of Polymer Translocation Events in Electrolyte Solutions
Date
2016Source Title
Journal of Chemical Physics
Print ISSN
0021-9606
Publisher
American Institute of Physics Inc.
Volume
145
Issue
1
Pages
1 - 12
Language
English
Type
ArticleItem Usage Stats
206
views
views
222
downloads
downloads
Abstract
We develop an analytical theory that accounts for the image and surface charge interactions between a charged dielectric membrane and a DNA molecule translocating through the membrane. Translocation events through neutral carbon-based membranes are driven by a competition between the repulsive DNA-image-charge interactions and the attractive coupling between the DNA segments on the trans and the cis sides of the membrane. The latter effect is induced by the reduction of the coupling by the dielectric membrane. In strong salt solutions where the repulsive image-charge effects dominate the attractive trans-cis coupling, the DNA molecule encounters a translocation barrier of ∼10 kBT. In dilute electrolytes, the trans-cis coupling takes over image-charge forces and the membrane becomes a metastable attraction point that can trap translocating polymers over long time intervals. This mechanism can be used in translocation experiments in order to control DNA motion by tuning the salt concentration of the solution.
Keywords
CarbonDNA
Electrolytes
Molecules
Polymers
Analytical theory
Charge interactions
Dielectric membranes
Electrolyte solutions
Image charge force
Image-charge effects
Polymer translocation
Salt concentration
Membranes
DNA
Electrolyte
Polymer
Solution and solubility
Algorithm
Cell membrane
Chemical model
Chemistry
Permeability
Solution and solubility
Static electricity
Algorithms
Cell Membrane
DNA
Electrolytes
Models, Chemical
Permeability
Polymers
Solutions
Static Electricity
Permalink
http://hdl.handle.net/11693/36651Published Version (Please cite this version)
http://dx.doi.org/10.1063/1.4954919Collections
Related items
Showing items related by title, author, creator and subject.
-
Tuning the degree of oxidation and electron delocalization of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) with solid-electrolyte
Vempati, Sesha; Ertaş, Yelda; Çelebioğlu, Aslı; Uyar, Tamer (Elsevier, 2017-10)We report on the effects of ionic interaction on the electronic structure of PEDOT:PSS where the oxidation state of PEDOT is an import aspect for various applications. Additional ionic interactions are introduced and ... -
Like-Charge Attraction And Opposite-Charge Decomplexation Between Polymers and DNA Molecules
Buyukdagli, S. (American Physical Society, 2017)We scrutinize the effect of polyvalent ions on polymer-DNA interactions. We extend a recently developed test-charge theory [S. Buyukdagli, Phys. Rev. E 94, 042502 (2016)1539-375510.1103/PhysRevE.94.042502] to the case of ... -
Ionic current inversion in pressure-driven polymer translocation through nanopores
Buyukdagli, S.; Blossey, R.; Ala-Nissila, T. (American Physical Society, 2015)We predict streaming current inversion with multivalent counterions in hydrodynamically driven polymer translocation events from a correlation-corrected charge transport theory including charge fluctuations around mean-field ...