Electrostatics of Polymer Translocation Events in Electrolyte Solutions

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dc.citation.epage12en_US
dc.citation.issueNumber1en_US
dc.citation.spage1en_US
dc.citation.volumeNumber145en_US
dc.contributor.authorBuyukdagli, S.en_US
dc.contributor.authorAla-Nissila, T.en_US
dc.date.accessioned2018-04-12T10:47:07Z
dc.date.available2018-04-12T10:47:07Z
dc.date.issued2016en_US
dc.departmentDepartment of Physicsen_US
dc.description.abstractWe develop an analytical theory that accounts for the image and surface charge interactions between a charged dielectric membrane and a DNA molecule translocating through the membrane. Translocation events through neutral carbon-based membranes are driven by a competition between the repulsive DNA-image-charge interactions and the attractive coupling between the DNA segments on the trans and the cis sides of the membrane. The latter effect is induced by the reduction of the coupling by the dielectric membrane. In strong salt solutions where the repulsive image-charge effects dominate the attractive trans-cis coupling, the DNA molecule encounters a translocation barrier of ∼10 kBT. In dilute electrolytes, the trans-cis coupling takes over image-charge forces and the membrane becomes a metastable attraction point that can trap translocating polymers over long time intervals. This mechanism can be used in translocation experiments in order to control DNA motion by tuning the salt concentration of the solution.en_US
dc.identifier.doi10.1063/1.4954919en_US
dc.identifier.issn0021-9606
dc.identifier.urihttp://hdl.handle.net/11693/36651
dc.language.isoEnglishen_US
dc.publisherAmerican Institute of Physics Inc.en_US
dc.relation.isversionofhttp://dx.doi.org/10.1063/1.4954919en_US
dc.source.titleJournal of Chemical Physicsen_US
dc.subjectCarbonen_US
dc.subjectDNAen_US
dc.subjectElectrolytesen_US
dc.subjectMoleculesen_US
dc.subjectPolymersen_US
dc.subjectAnalytical theoryen_US
dc.subjectCharge interactionsen_US
dc.subjectDielectric membranesen_US
dc.subjectElectrolyte solutionsen_US
dc.subjectImage charge forceen_US
dc.subjectImage-charge effectsen_US
dc.subjectPolymer translocationen_US
dc.subjectSalt concentrationen_US
dc.subjectMembranesen_US
dc.subjectDNAen_US
dc.subjectElectrolyteen_US
dc.subjectPolymeren_US
dc.subjectSolution and solubilityen_US
dc.subjectAlgorithmen_US
dc.subjectCell membraneen_US
dc.subjectChemical modelen_US
dc.subjectChemistryen_US
dc.subjectPermeabilityen_US
dc.subjectSolution and solubilityen_US
dc.subjectStatic electricityen_US
dc.subjectAlgorithmsen_US
dc.subjectCell Membraneen_US
dc.subjectDNAen_US
dc.subjectElectrolytesen_US
dc.subjectModels, Chemicalen_US
dc.subjectPermeabilityen_US
dc.subjectPolymersen_US
dc.subjectSolutionsen_US
dc.subjectStatic Electricityen_US
dc.titleElectrostatics of Polymer Translocation Events in Electrolyte Solutionsen_US
dc.typeArticleen_US
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