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dc.contributor.advisorTürkmen, Yunus Emre
dc.contributor.authorLiman, Menekşe
dc.date.accessioned2017-07-11T13:37:07Z
dc.date.available2017-07-11T13:37:07Z
dc.date.copyright2017-06
dc.date.issued2017-06
dc.date.submitted2017-07-04
dc.identifier.urihttp://hdl.handle.net/11693/33382
dc.descriptionCataloged from PDF version of article.en_US
dc.descriptionThesis (M.S.): Bilkent University, Department of Chemistry, İhsan Doğramacı Bilkent University, 2017.en_US
dc.descriptionIncludes bibliographical references (leaves 68-78).en_US
dc.description.abstractNitrogen-containing aromatic heterocycles, found in many biologically active natural products and pharmaceutical drugs, constitute a highly important class of compounds in organic chemistry. In this context, areas such as the discoveries of new synthetic methods for both the synthesis and derivatization of nitrogen-containing heterocyclic compounds as well as for the introduction of nitrogen to a compound attract significant attention in the areas of organic and pharmaceutical chemistry. In this study, we have developed a new one-pot synthetic method for the benzylic amination of azine-N-oxides containing a methyl group at the 2-position. Following the optimization studies, the substrate scope of the developed reaction has been investigated in detail. The reaction tolerates quinoline and isoquinoline N-oxides with electron donating and withdrawing substituents as the electrophilic reaction partner as well as a broad range of nucleophilic primary, secondary and aromatic amines.en_US
dc.description.statementofresponsibilityby Menekşe Liman.en_US
dc.format.extentxvii, 117 leaves : illustrations, charts (some color) ; 29 cm.en_US
dc.language.isoEnglishen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHeterocyclic compoundsen_US
dc.subjectAzine N-Oxidesen_US
dc.subjectBenzylic aminationen_US
dc.titleOne-pot, benzylic amination reactions of azine N-oxidesen_US
dc.title.alternativeAzin N-oksit bileşiklerinin benzilik aminasyonuen_US
dc.typeThesisen_US
dc.departmentDepartment of Chemistryen_US
dc.publisherBilkent Universityen_US
dc.description.degreeM.S.en_US
dc.identifier.itemidB155881
dc.embargo.release2018-07-04


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