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      Air-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgery

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      Author(s)
      Lanin, A.
      Fedotov, I. V.
      Sidorov Biryukov, D. S.
      Doronina Amitonova, L. V.
      Ivashkina, O. I.
      Zots, M. A.
      Sun, C. K.
      Ilday, F. O.
      Fedotov, A. B.
      Anokhin, K. V.
      Zheltikov, A. M.
      Date
      2012-03-06
      Source Title
      Applied Physics Letters
      Print ISSN
      0003-6951
      Publisher
      AIP Publishing LLC
      Volume
      100
      Issue
      10
      Pages
      101104-1 - 101104-4
      Language
      English
      Type
      Article
      Item Usage Stats
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      Abstract
      Large-core hollow photonic- crystal fibers (PCFs) are shown to enable a fiber-format air-guided delivery of ultrashort infrared laser pulses for neurosurgery and nonlinear-optical imaging. With an appropriate dispersion precompensation, an anomalously dispersive 15-mu m-core hollow PCF compresses 510-fs, 1070-nm light pulses to a pulse width of about 110 fs, providing a peak power in excess of 5 MW. The compressed PCF output is employed to induce a local photodisruption of corpus callosum tissues in mouse brain and is used to generate the third harmonic in brain tissues, which is captured by the PCF and delivered to a detector through the PCF cladding.
      Keywords
      Picosecond pulses
      Soliton output
      Microscopy
      Breakdown
      Permalink
      http://hdl.handle.net/11693/13222
      Published Version (Please cite this version)
      http://dx.doi.org/10.1063/1.3681777
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      • Department of Physics 2397
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