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      Design of synthetic biological devices for detection and targeting human diseases

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      Author(s)
      Hacıosmanoğlu, Nedim
      Köse, Sıla
      Ostaku, Julian
      Köksaldi, İlkay Çisil
      Saltepe, Behide
      Şeker, Urartu Özgür Şafak
      Editor
      Singh, V.
      Date
      2022-01-01
      Publisher
      Elsevier
      Pages
      251 - 269
      Language
      English
      Type
      Book Chapter
      Item Usage Stats
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      Book Title
      New Frontiers and Applications of Synthetic Biology
      Abstract
      Interpreting signals coming from the surrounding environment and responding to these stimuli by adjusting physical or metabolic state is the most fundamental ability of living organisms. Repurposing these natural abilities for the detection and responding to different molecules is one of the key focuses of synthetic biology because the overall strategy could provide advanced solutions for different diseases. Also by being naturally suitable to the design-build-test-learn manner of synthetic biology, biosensors are great examples of what engineering and biology could achieve when they come together. Literature has many examples of intellectually designed biosensor systems, which may overachieve and outperform existing technologies with a completely biocompatible structure. In this chapter, design and application of these biosensor systems will be investigated.
      Keywords
      Biosensors
      Cancer
      Infectious diseases
      Metabolic diseases
      Synthetic biology
      Toxicity
      Permalink
      http://hdl.handle.net/11693/111227
      Published Version (Please cite this version)
      https://doi.org/10.1016/B978-0-12-824469-2.00028-2
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      • Institute of Materials Science and Nanotechnology (UNAM) 2258
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