Design of synthetic biological devices for detection and targeting human diseases

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buir.contributor.authorHacıosmanoğlu, Nedim
buir.contributor.authorKöse, Sıla
buir.contributor.authorOstaku, Julian
buir.contributor.authorKöksaldi, İlkay Çisil
buir.contributor.authorSaltepe, Behide
buir.contributor.authorŞeker, Urartu Özgür Şafak
buir.contributor.orcidHacıosmanoğlu, Nedim|0000-0002-0696-6880
buir.contributor.orcidKöse, Sıla|0000-0003-1243-5602
buir.contributor.orcidOstaku, Julian|0000-0002-3648-1112
buir.contributor.orcidKöksaldi, İlkay Çisil|0000-0002-3121-4939
buir.contributor.orcidSaltepe, Behide|0000-0002-4338-6463
buir.contributor.orcidŞeker, Urartu Özgür Şafak|0000-0002-5272-1876
dc.citation.epage269en_US
dc.citation.spage251en_US
dc.contributor.authorHacıosmanoğlu, Nedim
dc.contributor.authorKöse, Sıla
dc.contributor.authorOstaku, Julian
dc.contributor.authorKöksaldi, İlkay Çisil
dc.contributor.authorSaltepe, Behide
dc.contributor.authorŞeker, Urartu Özgür Şafak
dc.contributor.editorSingh, V.
dc.date.accessioned2023-02-14T06:40:13Z
dc.date.available2023-02-14T06:40:13Z
dc.date.issued2022-01-01
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.description.abstractInterpreting signals coming from the surrounding environment and responding to these stimuli by adjusting physical or metabolic state is the most fundamental ability of living organisms. Repurposing these natural abilities for the detection and responding to different molecules is one of the key focuses of synthetic biology because the overall strategy could provide advanced solutions for different diseases. Also by being naturally suitable to the design-build-test-learn manner of synthetic biology, biosensors are great examples of what engineering and biology could achieve when they come together. Literature has many examples of intellectually designed biosensor systems, which may overachieve and outperform existing technologies with a completely biocompatible structure. In this chapter, design and application of these biosensor systems will be investigated.en_US
dc.identifier.doi10.1016/B978-0-12-824469-2.00028-2en_US
dc.identifier.isbn978-012824469-2
dc.identifier.urihttp://hdl.handle.net/11693/111227
dc.language.isoEnglishen_US
dc.publisherElsevieren_US
dc.relation.ispartofNew Frontiers and Applications of Synthetic Biologyen_US
dc.relation.isversionofhttps://doi.org/10.1016/B978-0-12-824469-2.00028-2en_US
dc.subjectBiosensorsen_US
dc.subjectCanceren_US
dc.subjectInfectious diseasesen_US
dc.subjectMetabolic diseasesen_US
dc.subjectSynthetic biologyen_US
dc.subjectToxicityen_US
dc.titleDesign of synthetic biological devices for detection and targeting human diseasesen_US
dc.typeBook Chapteren_US
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