Hybridization of fano and vibrational resonances in surface-enhanced infrared absorption spectroscopy of streptavidin monolayers on metamaterial substrates

Date
2014
Authors
Alici, K. B.
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Source Title
IEEE Transactions on Nanotechnology
Print ISSN
1536-125X
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Volume
13
Issue
2
Pages
216 - 221
Language
English
Type
Article
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Abstract

We present spectral hybridization of organic and inorganic resonant materials and related bio-sensing mechanism. We utilized a bound protein (streptavidin) and a Fano-resonant metasurface to illustrate the concept. The technique allows us to investigate the vibrational modes of the streptavidin and how they couple to the underlying metasurface. This optical, label-free, nonperturbative technique is supported by a coupled mode-theory analysis that provides information on the structure and orientation of bound proteins. We can also simultaneously monitor the binding of analytes to the surface through monitoring the shift of the metasurface resonance. All of this data opens up interesting opportunities for applications in biosensing, molecular electronics and proteomics. © 2014 IEEE.

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Keywords
Avidin, Biosensor, Biotin, Collective excitation, Enhancement factor, Fano resonance, Metamaterial, Microscopy, Monolayer, Nanoantenna, Near-field effects, Self-assembly, Spectroscopy, Streptavidin, Surface plasmon, Surface-enhanced infrared absorption (SEIRA), Temporal-coupled mode theory, Thin films, Avidin, Biotin, Collective excitations, Enhancement factor, Fano resonances, Mode theory, Nano antennas, Near field effect, Streptavidin, Surface plasmons, Surface-enhanced infrared absorptions, Biosensors, Light absorption, Metamaterials, Microscopic examination, Molecular biology, Monolayers, Resonance, Self assembly, Spectroscopy, Thin films, Proteins
Citation
Published Version (Please cite this version)