Temporal and spatial nonlinearities in FMRI BOLD response in human primary visual cortex

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buir.advisorBoyacı, Hüseyin
dc.contributor.authorBenar, Cem
dc.date.accessioned2019-08-06T09:47:12Z
dc.date.available2019-08-06T09:47:12Z
dc.date.copyright2019-07
dc.date.issued2019-07
dc.date.submitted2019-08-02
dc.descriptionCataloged from PDF version of article.en_US
dc.descriptionThesis (M.S.): Bilkent University, Department of Neuroscience, İhsan Doğramacı Bilkent University, 2019.en_US
dc.descriptionIncludes bibliographical references (leaves 130-138).en_US
dc.description.abstractIt is generally assumed that fMRI BOLD response (i.e., functional magnetic resonance imaging blood-oxygen-level-dependent signal) is linear and time-invariant. In this study, we investigated spatial and temporal nonlinearities in fMRI BOLD response at different flickering durations (nearly instantaneous and 1 s). We presented participants two successive flickering checkerboard wedge stimuli with stimulus onset asynchrony (SOA) of 0 s, 0.5 s, 1.5 s, and 6 s. The spatial locations of the stimuli were categorized as the same location in the same hemifield, adjacent locations in the same hemifield, and between hemifields. We demonstrated that fMRI BOLD response behaves nonlinearly when the successive stimuli spatially and temporally were close to each other for both flickering durations. Nonlinearity between the successive stimuli was the highest for the same location in the same hemifield, higher in adjacent locations in the same hemifield, and the lowest in between hemifields. In addition, nonlinearity at the shorter SOAs (0 s, 0.5 s, and 1.5 s) was found to be higher than nonlinearity at SOA 6.en_US
dc.description.provenanceSubmitted by Betül Özen (ozen@bilkent.edu.tr) on 2019-08-06T09:47:12Z No. of bitstreams: 1 cem_benar_21600443_msc_thesis.pdf: 34743805 bytes, checksum: 446cb5d96ca8cd5990d2c3aec19cae89 (MD5)en
dc.description.provenanceMade available in DSpace on 2019-08-06T09:47:12Z (GMT). No. of bitstreams: 1 cem_benar_21600443_msc_thesis.pdf: 34743805 bytes, checksum: 446cb5d96ca8cd5990d2c3aec19cae89 (MD5) Previous issue date: 2019-08en
dc.description.statementofresponsibilityby Cem Benaren_US
dc.format.extentxlviii, 219 leaves : illustrations, charts (some color) ; 30 cm.en_US
dc.identifier.itemidB157929
dc.identifier.urihttp://hdl.handle.net/11693/52297
dc.language.isoEnglishen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSpatial nonlinearityen_US
dc.subjectSpatial summationen_US
dc.subjectTemporal nonlinearityen_US
dc.subjectTemporal summationen_US
dc.subjectfMRI BOLDen_US
dc.subjectPrimary visual cortexen_US
dc.titleTemporal and spatial nonlinearities in FMRI BOLD response in human primary visual cortexen_US
dc.title.alternativeFMRG kan oksijen seviyesine bağımlı (BOLD) sinyalin insan birincil görme korteksinde zamansal ve konumsal nonlineerliklerien_US
dc.typeThesisen_US
thesis.degree.disciplineNeuroscience
thesis.degree.grantorBilkent University
thesis.degree.levelMaster's
thesis.degree.nameMS (Master of Science)

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