Relaxation-based color magnetic particle imaging for viscosity mapping

buir.contributor.authorUtkur, Mustafa
buir.contributor.authorMuslu, Yavuz
buir.contributor.authorSarıtaş, Emine Ülkü
dc.citation.epage152403-1en_US
dc.citation.issueNumber15en_US
dc.citation.spage152403-5en_US
dc.citation.volumeNumber115en_US
dc.contributor.authorUtkur, Mustafaen_US
dc.contributor.authorMuslu, Yavuzen_US
dc.contributor.authorSarıtaş, Emine Ülküen_US
dc.date.accessioned2020-02-12T12:09:02Z
dc.date.available2020-02-12T12:09:02Z
dc.date.issued2019
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentInterdisciplinary Program in Neuroscience (NEUROSCIENCE)en_US
dc.departmentNational Magnetic Resonance Research Center (UMRAM)en_US
dc.departmentAysel Sabuncu Brain Research Center (BAM)en_US
dc.description.abstractMagnetic particle imaging (MPI) uses superparamagnetic iron oxide (SPIO) nanoparticles as biomedical imaging tracers. The potential applications of MPI have recently been broadened by the introduction of “color” MPI techniques that can distinguish different nanoparticles and/or environments, e.g., by exploiting the relaxation behavior of SPIOs. One of the important applications of color MPI techniques is viscosity mapping. In this work, we show relaxation-based color MPI experiments that can distinguish the biologically relevant viscosity range of up to 5 mPa s. To find the optimal drive field parameters for viscosity, we compare color MPI results at three different frequencies. We show that frequencies around 10 kHz are well-suited for viscosity mapping using the multicore cluster Nanomag-MIP nanoparticles, providing a one-to-one mapping between the estimated relaxation time constant and viscosity.en_US
dc.description.provenanceSubmitted by Zeynep Aykut (zeynepay@bilkent.edu.tr) on 2020-02-12T12:09:02Z No. of bitstreams: 1 Relaxation_based_color_magnetic_particle_imaging_for_viscosity_mapping.pdf: 1074839 bytes, checksum: fe035d47a203baac70f88806f22c85e1 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-02-12T12:09:02Z (GMT). No. of bitstreams: 1 Relaxation_based_color_magnetic_particle_imaging_for_viscosity_mapping.pdf: 1074839 bytes, checksum: fe035d47a203baac70f88806f22c85e1 (MD5) Previous issue date: 2019en
dc.identifier.doi10.1063/1.5110475en_US
dc.identifier.issn0003-6951
dc.identifier.urihttp://hdl.handle.net/11693/53313
dc.language.isoEnglishen_US
dc.publisherAmerican Institute of Physicsen_US
dc.relation.isversionofhttps://dx.doi.org/10.1063/1.5110475en_US
dc.source.titleApplied Physics Lettersen_US
dc.subjectElectromagnetic coilsen_US
dc.subjectRelaxation methoden_US
dc.subjectMedical imagingen_US
dc.subjectImage processingen_US
dc.subjectViscosity measurementsen_US
dc.subjectNanoparticlesen_US
dc.titleRelaxation-based color magnetic particle imaging for viscosity mappingen_US
dc.typeArticleen_US

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