mESAdb: microRNA expression and sequence analysis database

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buir.contributor.authorKaya, Koray D.
buir.contributor.authorYakıcıer, Cengiz M.
buir.contributor.authorAcar, Aybar C.
buir.contributor.authorKonu, Özlen
dc.citation.epageD180en_US
dc.citation.spageD170en_US
dc.citation.volumeNumber39en_US
dc.contributor.authorKaya, Koray D.en_US
dc.contributor.authorKarakülah, G.en_US
dc.contributor.authorYakıcıer, Cengiz M.en_US
dc.contributor.authorAcar, Aybar C.en_US
dc.contributor.authorKonu, Özlenen_US
dc.date.accessioned2016-02-08T09:54:53Z
dc.date.available2016-02-08T09:54:53Z
dc.date.issued2011en_US
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.departmentDepartment of Computer Engineeringen_US
dc.departmentGenetics and Biotechnology Research Center (BİLGEN)en_US
dc.description.abstractMicroRNA expression and sequence analysis database (http://konulab.fen. bilkent.edu.tr/mirna/) (mESAdb) is a regularly updated database for the multivariate analysis of sequences and expression of microRNAs from multiple taxa. mESAdb is modular and has a user interface implemented in PHP and JavaScript and coupled with statistical analysis and visualization packages written for the R language. The database primarily comprises mature microRNA sequences and their target data, along with selected human, mouse and zebrafish expression data sets. mESAdb analysis modules allow (i) mining of microRNA expression data sets for subsets of microRNAs selected manually or by motif; (ii) pair-wise multivariate analysis of expression data sets within and between taxa; and (iii) association of microRNA subsets with annotation databases, HUGE Navigator, KEGG and GO. The use of existing and customized R packages facilitates future addition of data sets and analysis tools. Furthermore, the ability to upload and analyze user-specified data sets makes mESAdb an interactive and expandable analysis tool for microRNA sequence and expression data.en_US
dc.description.provenanceMade available in DSpace on 2016-02-08T09:54:53Z (GMT). No. of bitstreams: 1 bilkent-research-paper.pdf: 70227 bytes, checksum: 26e812c6f5156f83f0e77b261a471b5a (MD5) Previous issue date: 2011en
dc.identifier.doi10.1093/nar/gkq1256en_US
dc.identifier.eissn1362-4962en_US
dc.identifier.issn0305-1048en_US
dc.identifier.urihttp://hdl.handle.net/11693/22055
dc.language.isoEnglishen_US
dc.publisherOxford University Pressen_US
dc.relation.isversionofhttp://dx.doi.org/10.1093/nar/gkq1256en_US
dc.source.titleNucleic Acids Researchen_US
dc.subjectComputer interfaceen_US
dc.subjectGene expressionen_US
dc.subjectGene functionen_US
dc.subjectGenetic associationen_US
dc.subjectInformation processingen_US
dc.subjectMicroRNA expression and sequence analysis databaseen_US
dc.subjectPriority journalen_US
dc.subjectRNA sequenceen_US
dc.subjectSequence analysisen_US
dc.subjectSequence databaseen_US
dc.subjectStatistical analysisen_US
dc.subjectAnimalsen_US
dc.subjectDatabasesen_US
dc.subjectHumansen_US
dc.subjectMiceen_US
dc.subjectMicroRNAsen_US
dc.subjectSoftwareen_US
dc.subjectSystems Integrationen_US
dc.subjectDanio rerioen_US
dc.titlemESAdb: microRNA expression and sequence analysis databaseen_US
dc.typeArticleen_US

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