Ultrafast and sensitive bioassay using split ring resonator structures and microwave heating

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buir.contributor.authorÖzbay, Ekmel
buir.contributor.orcidÖzbay, Ekmel|0000-0003-2953-1828
dc.citation.epage093701-3en_US
dc.citation.issueNumber9en_US
dc.citation.spage093701-1en_US
dc.citation.volumeNumber97en_US
dc.contributor.authorCaglayan, H.en_US
dc.contributor.authorCakmakyapan, S.en_US
dc.contributor.authorAddae, S. A.en_US
dc.contributor.authorPinard, M. A.en_US
dc.contributor.authorCaliskan, D.en_US
dc.contributor.authorAslan, K.en_US
dc.contributor.authorÖzbay, Ekmelen_US
dc.date.accessioned2015-07-28T11:59:28Z
dc.date.available2015-07-28T11:59:28Z
dc.date.issued2010-08-30en_US
dc.departmentDepartment of Physicsen_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentNanotechnology Research Center (NANOTAM)en_US
dc.description.abstractIn this paper, we have reported that split ring resonators (SRRs) structures can be used for bioassay applications in order to further improve the assay time and sensitivity. The proof-of-principle demonstration of the ultrafast bioassays was accomplished by using a model biotin-avidin bioassay. While the identical room temperature bioassay (without microwave heating) took 70 min to complete, the identical bioassay took less than 2 min to complete by using SRR structures (with microwave heating). A lower detection limit of 0.01 nM for biotinylated-bovine serum albumin (100-fold lower than the room temperature bioassay) was observed by using SRR structures.en_US
dc.description.provenanceMade available in DSpace on 2015-07-28T11:59:28Z (GMT). No. of bitstreams: 1 10.1063-1.3484958.pdf: 338020 bytes, checksum: f3e8722d917d70f32a5f5f53aeecbf6d (MD5)en
dc.identifier.doi10.1063/1.3484958en_US
dc.identifier.issn0003-6951
dc.identifier.urihttp://hdl.handle.net/11693/11969
dc.language.isoEnglishen_US
dc.publisherAmerican Institute of Physicsen_US
dc.relation.isversionofhttp://dx.doi.org/10.1063/1.3484958en_US
dc.source.titleApplied Physics Lettersen_US
dc.subjectMagnetic-resonanceen_US
dc.subjectMetamaterialen_US
dc.subjectSubstrateen_US
dc.subjectAntennaen_US
dc.subjectCompacten_US
dc.titleUltrafast and sensitive bioassay using split ring resonator structures and microwave heatingen_US
dc.typeArticleen_US

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