Hadamard slice encoding for reduced-FOV diffusion-weighted imaging

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buir.contributor.authorSarıtaş, Emine Ülkü
buir.contributor.authorÇukur, Tolga
dc.citation.epage1290en_US
dc.citation.issueNumber5en_US
dc.citation.spage1277en_US
dc.citation.volumeNumber72en_US
dc.contributor.authorSarıtaş, Emine Ülküen_US
dc.contributor.authorLee, D.en_US
dc.contributor.authorÇukur, Tolgaen_US
dc.contributor.authorShankaranarayanan, A.en_US
dc.contributor.authorNishimura, D. G.en_US
dc.date.accessioned2016-02-08T11:02:32Z
dc.date.available2016-02-08T11:02:32Z
dc.date.issued2014en_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentAysel Sabuncu Brain Research Center (BAM)en_US
dc.description.abstractMethods: A 2D echo-planar RF pulse and matching multiband refocusing RF pulses were designed using the Shinnar-Le Roux algorithm to reduce band interference, and variable-rate selective excitation to shorten the pulse durations. Hadamardencoded images were resolved through a phase-preserving image reconstruction. The performance of the method was evaluated via simulations, phantom experiments, and in vivo high-resolution axial DWI of spinal cord.Purpose: To improve the clinical utility of diffusion-weighted imaging (DWI) by extending the slice coverage of a highresolution reduced field-of-view technique. Theory: Challenges in achieving high spatial resolution restrict the use of DWI in assessment of small structures such as the spinal cord. A reduced field-of-view method with 2D echo-planar radiofrequency (RF) excitation was recently proposed for high-resolution DWI. Here, a Hadamard sliceencoding scheme is proposed to double the slice coverage by exploiting the periodicity of the 2D echo-planar RF excitation profile.Results: The proposed scheme successfully extends the slice coverage, while preserving the sharp excitation profile and the reliable fat suppression of the original method. For in vivo axial DWI of the spinal cord, an in-plane resolution of 0.7 × 0.7 mm2 was achieved with 16 slices.Conclusion: The proposed Hadamard slice-encoding scheme doubles the slice coverage of the 2D echo-planar RF reduced field-of-view method without any scan-time penalty.en_US
dc.identifier.doi10.1002/mrm.25044en_US
dc.identifier.eissn1522-2594
dc.identifier.issn0740-3194
dc.identifier.urihttp://hdl.handle.net/11693/26625
dc.language.isoEnglishen_US
dc.publisherJohn Wiley & Sonsen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/mrm.25044en_US
dc.source.titleMagnetic Resonance in Medicineen_US
dc.subjectdiffusion-weighted imagingen_US
dc.subjectHadamard encodingen_US
dc.subjectMultiband excitationen_US
dc.subjectReduced field-of-viewen_US
dc.subject2D RF pulseen_US
dc.titleHadamard slice encoding for reduced-FOV diffusion-weighted imagingen_US
dc.typeArticleen_US

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Department of Electrical and Electronics Engineering
Aysel Sabuncu Brain Research Center (BAM)