Mesenchymal Stem Cells: Possibilities of New Treatment Options

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dc.citation.epage67en_US
dc.citation.spage59en_US
dc.contributor.authorTokcaer-Keskin, Z.en_US
dc.contributor.authorKocak, H.en_US
dc.contributor.authorGursel, I.en_US
dc.contributor.authorAkcali, K. C.en_US
dc.date.accessioned2018-04-12T13:53:56Z
dc.date.available2018-04-12T13:53:56Z
dc.date.issued2012en_US
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.description.abstractStem cell research evolved as a new hope and has gained tremendous interest during the last two decades in developing potential strategies for many debilitating diseases. Mesenchymal stem cells (MSCs) are bone marrow-derived multipotent stem cells capable of self-renewal and of differentiating into multiple lineages, such as osteocytes, adipocytes, chondrocytes, myoblasts, cardiomyocytes, and hepatocytes. MSCs are an important source for cellular therapies. They can easily be obtained and expanded in vitro in large numbers without significantly altering their properties. MSCs not only migrate to the injured site in vivo but also have immunomodulatory effects that make their use attractive for allogeneic grafting. MSCs can also be frozen for preservation; and when thawed, they retain their normal physiological function, allowing future ''off-the-shelf'' therapy approaches. Because of these features, MSCs have high therapeutic value in tissue engineering and regenerative medicine. In this chapter, the contribution of the MSCs to cardiovascular repair and liver regeneration are summarized.en_US
dc.description.provenanceMade available in DSpace on 2018-04-12T13:53:56Z (GMT). No. of bitstreams: 1 bilkent-research-paper.pdf: 179475 bytes, checksum: ea0bedeb05ac9ccfb983c327e155f0c2 (MD5) Previous issue date: 2012en
dc.identifier.doi10.1007/978-1-61779-630-2_6en_US
dc.identifier.isbn9781617796302
dc.identifier.isbn9781617796296
dc.identifier.urihttp://hdl.handle.net/11693/38356
dc.language.isoEnglishen_US
dc.publisherHumana Press Inc.en_US
dc.relation.isversionofhttp://dx.doi.org/10.1007/978-1-61779-630-2_6en_US
dc.source.titleAdult and Embryonic Stem Cellsen_US
dc.titleMesenchymal Stem Cells: Possibilities of New Treatment Optionsen_US
dc.typeBook Chapteren_US

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