Contrast enhancement of microscopy images using image phase information

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buir.contributor.authorÇetin, A. Enis
buir.contributor.authorÇakır, Serdar
buir.contributor.authorKahraman, Deniz Cansen
buir.contributor.authorÇetin-Atalay, Rengül
buir.contributor.orcidÇetin, A. Enis|0000-0002-3449-1958
dc.citation.epage3850en_US
dc.citation.spage3839en_US
dc.citation.volumeNumber6en_US
dc.contributor.authorÇakır, Serdaren_US
dc.contributor.authorKahraman, Deniz Cansenen_US
dc.contributor.authorÇetin-Atalay, Rengülen_US
dc.contributor.authorÇetin, A. Enisen_US
dc.date.accessioned2019-02-21T16:04:04Z
dc.date.available2019-02-21T16:04:04Z
dc.date.issued2018en_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.description.abstractContrast enhancement is an important preprocessing step for the analysis of microscopy images. The main aim of contrast enhancement techniques is to increase the visibility of the cell structures and organelles by modifying the spatial characteristics of the image. In this paper, phase information-based contrast enhancement framework is proposed to overcome the limitations of existing image enhancement techniques. Inspired by the groundbreaking design of the phase contrast microscopy (PCM), the proposed image enhancement framework transforms the changes in image phase into the variations of magnitude to enhance the structural details of the image and to improve visibility. In addition, the concept of selective variation (SV) technique is introduced and enhancement parameters are optimized using SV. The experimental studies that were carried out on microscopy images show that the proposed scheme outperforms the baseline enhancement frameworks. The contrast enhanced images produced by the proposed method have comparable cellular texture structure as PCM images.
dc.description.sponsorshipThis work was supported by the Turkish Ministry of Development under KanSiL_2016K121540 Project.
dc.identifier.doi10.1109/ACCESS.2018.2796646
dc.identifier.issn2169-3536
dc.identifier.urihttp://hdl.handle.net/11693/50158
dc.language.isoEnglish
dc.publisherInstitute of Electrical and Electronics Engineers
dc.relation.isversionofhttps://doi.org/10.1109/ACCESS.2018.2796646
dc.rightsinfo:eu-repo/semantics/openAccess
dc.source.titleIEEE Accessen_US
dc.subjectcontrast enhancementen_US
dc.subjectFourier transformen_US
dc.subjectImage phase informationen_US
dc.subjectMicroscopy imagesen_US
dc.subjectPhase contrast microscopyen_US
dc.titleContrast enhancement of microscopy images using image phase informationen_US
dc.typeArticleen_US

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