Tetrastyryl-BODIPY dyes as potential photosensitizers for photodynamic theraphy

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buir.advisorAkkaya, Engin U.
dc.contributor.authorYeşilgül, Nisa
dc.date.accessioned2016-01-08T18:24:12Z
dc.date.available2016-01-08T18:24:12Z
dc.date.issued2011
dc.descriptionAnkara : The Department of Chemistry and the Graduate School of Engineering and Science of Bilkent University, 2011.en_US
dc.descriptionThesis (Master's) -- Bilkent University, 2011.en_US
dc.descriptionIncludes bibliographical references leaves 42-45.en_US
dc.description.abstractPhotodynamic therapy (PDT) is a novel methodology for a wide range of treatments of cancerous and noncancerous diseases. Success of treatment and photodynamic action is highly dependent the performance of PDT agents. Therefore, PDT agents with unique photophysical properties are required in clinical applications. There are several photosensitizers in literature and some are available. However, most of them less than ideal due to limitations such as low molar absorptivity and photo stabilities. In this study, we synthesized near-IR tetrastyryl-Bodipy derivatives as photosensitizers. These sensitizers have strong absorption in therapeutic region and are good photo-generator of singlet oxygen. They are promising for photodynamic therapy with their favorable properties.en_US
dc.description.provenanceMade available in DSpace on 2016-01-08T18:24:12Z (GMT). No. of bitstreams: 1 0006466.pdf: 2742577 bytes, checksum: f650ceb932ec420ca772ec3fbc393f58 (MD5)en
dc.description.statementofresponsibilityYeşilgül, Nisaen_US
dc.format.extentxiv, 58 leaves, illustrationsen_US
dc.identifier.itemidB130524
dc.identifier.urihttp://hdl.handle.net/11693/15758
dc.language.isoEnglishen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBoradiazaindacene (Bodipy)en_US
dc.subjectPhotodynamic therapy (PDT)en_US
dc.subjectPhotosensitizer (PS)en_US
dc.subjectSinglet oxygenen_US
dc.subject.lccQZ267 .Y47 2011en_US
dc.subject.lcshPhotochemotherapy.en_US
dc.subject.lcshPhotosensitizing Agents--therapeutic use.en_US
dc.subject.lcshNanostructured materials.en_US
dc.subject.lcshPhototherapy.en_US
dc.titleTetrastyryl-BODIPY dyes as potential photosensitizers for photodynamic theraphyen_US
dc.typeThesisen_US
thesis.degree.disciplineChemistry
thesis.degree.grantorBilkent University
thesis.degree.levelMaster's
thesis.degree.nameMS (Master of Science)

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