Response surface optimization of the cultivation conditions and medium composition a novel probiotic strain Bacillus pumilus STF26

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dc.citation.epage1361en_US
dc.citation.issueNumber4en_US
dc.citation.spage1355en_US
dc.citation.volumeNumber21en_US
dc.contributor.authorHan, D.en_US
dc.contributor.authorSan, N. O.en_US
dc.contributor.authorAngun, P.en_US
dc.contributor.authorOnarman Umu, O. C.en_US
dc.contributor.authorDemirci, A.en_US
dc.contributor.authorTekinay, T.en_US
dc.date.accessioned2016-02-08T10:59:11Z
dc.date.available2016-02-08T10:59:11Z
dc.date.issued2014en_US
dc.departmentInstitute of Materials Science and Nanotechnology (UNAM)en_US
dc.description.abstractProbiotics have been widely used in aquaculture as a controlling disease, enhancing immune responses, providing nutrients, and improving water quality. The use of Bacillus species as probiotics is expanding rapidly with increasing number of studies. Optimization of cultivation conditions and the medium composition for the improvement of novel potential probiotic strain Bacillus pumilus STF26 was performed by using response surface methodology (RSM). Factors optimized were temperature, pH and the concentrations of dextrose, yeast extract, KH2PO4 and MgSO4.7H2O. The optimum values are found as 30.9°C, 6.9, 20% (w/v), for temperature, pH and the concentrations of dextrose and 1.526% (w/v), 0.1% (w/v) and 0.5% (w/v), for yeast extract, KH2PO4 and MgSO4.7H2O, respectively. As a result, maximum biomass at optimum conditions was 10.42 g/L, which is nearly 2.5 times higher when compared to the one obtained by using Luria Broth medium at optimized temperature and pH values. © All Rights Reserved.en_US
dc.identifier.issn1985-4668
dc.identifier.urihttp://hdl.handle.net/11693/26394
dc.language.isoEnglishen_US
dc.publisherUniversiti Putra Malaysiaen_US
dc.source.titleInternational Food Research Journalen_US
dc.subjectBacillus pumilusen_US
dc.subjectMethodologyen_US
dc.subjectOptimizationen_US
dc.subjectProbioticsen_US
dc.subjectResponse surfaceen_US
dc.titleResponse surface optimization of the cultivation conditions and medium composition a novel probiotic strain Bacillus pumilus STF26en_US
dc.typeArticleen_US

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Institute of Materials Science and Nanotechnology (UNAM)