A microfluidic based differential plasmon resonance sensor

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dc.citation.epage676en_US
dc.citation.issueNumber1en_US
dc.citation.spage670en_US
dc.citation.volumeNumber160en_US
dc.contributor.authorOkan, M.en_US
dc.contributor.authorBalci, O.en_US
dc.contributor.authorKocabas, C.en_US
dc.date.accessioned2016-02-08T09:49:20Z
dc.date.available2016-02-08T09:49:20Z
dc.date.issued2011en_US
dc.departmentDepartment of Physicsen_US
dc.description.abstractA new type of differential surface plasmon (SPR) sensor integrated with a microfluidic system is presented. The working principle of the microfluidic device is based on hydrodynamic modulation of two laminar streams inside a microchannel to provide periodic changes of the environment on the SPR sensor. The modulated reflectance is then demodulated using a lock-in amplifier. The presented sensor provides sensitivities of index of refraction about 4 × 10-8 RIU together with a 4 orders of magnitude dynamic range. This method demonstrates a sensitive detection scheme which could be used for label-free detection. © 2011 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.snb.2011.08.046en_US
dc.identifier.eissn1873-3077
dc.identifier.issn0925-4005
dc.identifier.urihttp://hdl.handle.net/11693/21655
dc.language.isoEnglishen_US
dc.publisherElsevieren_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.snb.2011.08.046en_US
dc.source.titleSensors and Actuators, B: Chemicalen_US
dc.subjectSurface plasmon resonance sensoren_US
dc.subjectPhase sensitive detectionen_US
dc.subjectLab-on-a-chip systemsen_US
dc.subjectMicrofluidic devicesen_US
dc.subjectOptical sensorsen_US
dc.titleA microfluidic based differential plasmon resonance sensoren_US
dc.typeArticleen_US

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